Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Income Statement [Abstract]
Collaboration revenue	$ 195	$ 544	$ 1,325	$ 1,412
Operating expenses:
Research and development	5,902	12,368	37,404	35,763
General and administrative	3,931	5,003	14,888	14,700
Impairment of property and equipment	1,900		1,883	1,592
Impairment of right-of-use assets			22,836
Restructuring and other related charges	2,804		9,254
Total operating expenses	12,637	17,371	86,265	52,055
Loss from operations	(12,442)	(16,827)	(84,940)	(50,643)
Other income:
Interest income	576	1,192	2,517	3,161
Total other income	576	1,192	2,517	3,161
Loss before income tax expense	(11,866)	(15,635)	(82,423)	(47,482)
Income tax expense	(7)	(16)	(33)	(42)
Net loss	(11,873)	(15,651)	(82,456)	(47,524)
Unrealized holding gain (loss) on short-term investments, net of tax	24	20	(13)	(17)
Comprehensive loss	$ (11,849)	$ (15,631)	$ (82,469)	$ (47,541)
Net loss per share attributable to common stockholders- basic	$ (0.18)	$ (0.27)	$ (1.27)	$ (1.04)
Net loss per share attributable to common stockholders- diluted	$ (0.18)	$ (0.27)	$ (1.27)	$ (1.04)
Weighted-average common shares outstanding-basic	65,456,735	56,953,685	64,981,219	45,894,643
Weighted-average common shares outstanding-diluted	65,456,735	56,953,685	64,981,219	45,894,643