Organization, Restructuring, Going Concern and Basis of Presentation - Additional Information (Details) $ in Thousands				2 Months Ended	3 Months Ended	6 Months Ended
	Mar. 22, 2024 USD ($)	May 25, 2023 USD ($)	Apr. 13, 2022 USD ($)	Jun. 30, 2024 USD ($) Employee	Jun. 30, 2024 USD ($)	Jun. 30, 2024 USD ($) Lease	Dec. 31, 2023 USD ($)
Organization And Basis Of Presentation [Line Items]
Entity incorporation, date of incorporation						Nov. 21, 2005
Restructuring charge					$ 6,450	$ 6,450
Impairment charge for write-down of property and equipment						1,900
Impairment Of Right Of Use Asset					22,836	22,836
Fund raised for operations						424,800
Proceeds from issuance of redeemable convertible preferred stock						162,100
Proceeds from issuance initial public offering						57,300
Accumulated deficit				$ (381,938)	(381,938)	(381,938)	$ (311,355)
Cash and cash equivalents				31,905	31,905	31,905	22,353
Short-term investments				$ 35,593	$ 35,593	35,593	$ 80,400
Proceeds from government contracts						16,800
Gross proceeds for warrant exercises						3,800
Proceeds from license and collaboration agreement						$ 17,000
Stock and warrants to be issued during period value preferred stock and warrants	$ 300,000
Number of leased properties marketed for sublease arrangements | Lease						3
Private Placement
Organization And Basis Of Presentation [Line Items]
Net proceeds from private placement			$ 96,300			$ 96,300
Private Placement | Purchase Agreement
Organization And Basis Of Presentation [Line Items]
Net proceeds from private placement		$ 50,000
Net proceeds from issuance of preferred stock allocated to warrants		46,500				46,500
Private Placement | Pre Funded Warrants
Organization And Basis Of Presentation [Line Items]
Gross proceeds for warrant exercises			$ 21,100
Controlled Equity Offering Sales Agreement
Organization And Basis Of Presentation [Line Items]
Net proceeds						$ 23,900
Employee Severance [Member]
Organization And Basis Of Presentation [Line Items]
Number of employees reduced | Employee				87
Common Stock
Organization And Basis Of Presentation [Line Items]
Net proceeds		$ 30,500