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Collaboration Agreement - Additional Information (Details) - USD ($)
1 Months Ended 12 Months Ended
May 31, 2021
Feb. 28, 2022
Dec. 31, 2023
Dec. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Future milestone payments receivable $ 135,000,000      
Collaboration revenue     $ 1,558,000 $ 1,363,000
Combined performance obligation     8,400,000  
Development activities performance obligation     $ 3,600,000  
Deferred revenue, description     Under the LianBio License Agreement, in order to evaluate the transaction price for purposes of ASC 606, the Company determined that the upfront payment of $12.0 million and the reimbursable cost of the clinical supply of LYR-210 constitute the entirety of the consideration to be included in the transaction price as of the outset of the arrangement, which was allocated to the two performance obligations as follows: $8.4 million to the Combined Performance Obligation and $3.6 million to the Development Activities Performance Obligation. In February 2022, the Company received $5.0 million upon achievement of the first of the development milestones related to dosing its first patient and the transaction price was adjusted by $5.0 million which was allocated to the two performance obligations as follows: $3.5 million to the Combined Performance Obligation and $1.5 million to the Development Activities Performance Obligation. The remaining potential milestone payments that the Company is eligible to receive were excluded from the transaction price as of December 31, 2023, as all milestone amounts were fully constrained based on the probability of achievement.  
Clinical Supply Agreement        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Upfront payment received $ 12,000,000      
Upfront payment recognition in future periods to settlement of obligation     $ 12,000,000  
Milestone Achievements        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Collaboration revenue   $ 5,000,000 0 $ 5,000,000
Upfront payment recognition in future periods to settlement of obligation   5,000,000 5,000,000  
Combined performance obligation   3,500,000 3,489,000  
Development activities performance obligation     1,511,000  
Pre-Milestone        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Upfront payment recognition in future periods to settlement of obligation   12,000,000 12,000,000  
Combined performance obligation     8,373,000  
Development activities performance obligation     3,627,000  
Post-Milestone        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]        
Upfront payment recognition in future periods to settlement of obligation   $ 17,000,000 17,000,000  
Combined performance obligation     11,862,000  
Development activities performance obligation     $ 5,138,000