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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Cash flows from operating activities:    
Net loss $ (16,255) $ (11,911)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 1,610 844
Depreciation expense 284 280
Net amortization of premium on short-term investments (726)  
Changes in operating assets and liabilities:    
Collaboration revenue receivable   (5,000)
Prepaid expenses and other current assets 843 371
Operating lease right-of-use assets 398 246
Other assets (2,446) (260)
Accounts payable 3,295 (663)
Accrued expenses and other current liabilities (2,318) (87)
Operating lease liabilities (125) (257)
Deferred revenue (410) 4,532
Net cash used in operating activities (15,850) (11,905)
Cash flows from investing activities:    
Purchases of property and equipment (45) (93)
Purchases of short-term investments (4,440)  
Maturity of short-term investments 9,800  
Net cash provided by (used in) investing activities 5,315 (93)
Cash flows from financing activities:    
Payment of deferred offering expenses   (2)
Proceeds from exercise of stock options 4 8
Net cash provided by financing activities 4 6
Net decrease in cash, cash equivalents and restricted cash (10,531) (11,992)
Cash, cash equivalents and restricted cash, beginning of period 33,942 46,076
Cash, cash equivalents and restricted cash, end of period $ 23,411 $ 34,084