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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash flows from operating activities:    
Net loss $ (55,278,000) $ (43,513,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 5,447,000 2,770,000
Depreciation expense 1,067,000 1,001,000
Loss on impairment of long-lived assets 1,316,000 0
Net amortization of premium on short-term investments (492,000)  
Changes in assets and liabilities:    
Prepaid expenses and other current assets (764,000) (847,000)
Operating lease right-of-use assets (868,000) 946,000
Other assets (574,000) (500,000)
Accounts payable (2,411,000) 2,350,000
Accrued expenses and other current liabilities 4,772,000 1,244,000
Operating lease liabilities 763,000 (986,000)
Deferred revenue 3,637,000 11,715,000
Net cash used in operating activities (43,385,000) (25,820,000)
Cash flows from investing activities:    
Purchases of property and equipment (164,000) (3,385,000)
Purchase of investments (64,842,000)  
Net cash used in investing activities (65,006,000) (3,385,000)
Cash flows from financing activities:    
Proceeds from sale of common stock and pre-funded warrants 100,495,000  
Payment of deferred offering expenses (4,246,000) (245,000)
Proceeds from exercise of stock options 8,000 604,000
Net cash provided by financing activities 96,257,000 359,000
Net decrease in cash, cash equivalents and restricted cash (12,134,000) (28,846,000)
Cash and cash equivalents and restricted cash, beginning of period 46,076,000 74,922,000
Cash and cash equivalents and restricted cash, end of period 33,942,000 46,076,000
Supplemental disclosure of non-cash financing and investing activities:    
Property and equipment purchases included in accounts payable   41,000
Other Assets Included in Accounts Payable and Accrued Expenses 1,960,000 15,000
Modification of lease agreement $ 1,928,000  
Deferred offering costs included in accounts payable and accrued expense   $ 2,000