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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities:    
Net loss $ (11,911,000) $ (7,802,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 844,000 599,000
Depreciation expense 280,000 70,000
Changes in operating assets and liabilities:    
Collaboration revenue receivable (5,000,000)  
Prepaid expenses and other current assets 371,000 78,000
Operating lease right-of-use assets 246,000 232,000
Other assets (260,000)  
Accounts payable (663,000) 452,000
Accrued expenses and other current liabilities (87,000) (983,000)
Operating lease liabilities (257,000) (236,000)
Deferred revenue 4,532,000  
Net cash used in operating activities (11,905,000) (7,590,000)
Cash flows from investing activities:    
Purchases of property and equipment (93,000) (1,160,000)
Net cash used in investing activities (93,000) (1,160,000)
Cash flows from financing activities:    
Payment of deferred offering expenses (2,000)  
Proceeds from exercise of stock options 8,000 262,000
Net cash provided by financing activities 6,000 262,000
Net decrease in cash and cash equivalents (11,992,000) (8,488,000)
Cash and cash equivalents and restricted cash, beginning of period 46,076,000 74,922,000
Cash and cash equivalents and restricted cash, end of period 34,084,000 $ 66,434,000
Supplemental disclosure of non-cash financing and investing activities:    
Deferred offering costs included in accounts payable and accrued expense $ 68,000