Organization and Basis of Presentation - Additional Information (Details) $ in Thousands			3 Months Ended		196 Months Ended
	Apr. 13, 2022 USD ($)	Mar. 11, 2020 Patient	Mar. 31, 2022 USD ($)	Mar. 31, 2021 USD ($)	Mar. 31, 2022 USD ($)	Dec. 31, 2022	Dec. 31, 2021 USD ($)
Organization And Basis Of Presentation [Line Items]
Entity incorporation, date of incorporation			Nov. 21, 2005
Fund raised for operations					$ 249,100
Proceeds from sales of redeemable convertible preferred stock					162,100
Proceeds from government contracts					16,800
Proceeds from license and collaboration agreement					12,000
Net losses			$ 11,911	$ 7,802
Accumulated deficit			(205,308)		(205,308)		$ (193,397)
Cash and cash equivalents			$ 33,755		33,755		$ 45,747
Number of patients | Patient		67
Employer side social security payments due, percentage						50.00%	50.00%
Private Placement | Subsequent Event
Organization And Basis Of Presentation [Line Items]
Gross proceeds from private placement	$ 100,500
Common Stock
Organization And Basis Of Presentation [Line Items]
Net proceeds from initial public offering					$ 57,300