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Leases - Agreements (Details)
1 Months Ended 12 Months Ended
Jul. 14, 2021
USD ($)
ft²
uSDollarPerSquareFoot
Aug. 31, 2022
USD ($)
uSDollarPerSquareFoot
Jun. 30, 2021
ft²
phase
Dec. 31, 2022
USD ($)
lease
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Jul. 01, 2025
USD ($)
ft²
Lessee, Lease, Description [Line Items]              
Addition of right-of-use asset       $ 6,155,000 $ 24,047,000 $ 3,127,000  
Monrovia, CA - office and laboratory space              
Lessee, Lease, Description [Line Items]              
Number of leases | lease       2      
Option to extend       true      
Renewal term       5 years      
Addition of right-of-use asset       $ 300,000      
Monrovia, CA - office and laboratory space with additional space              
Lessee, Lease, Description [Line Items]              
Addition of right-of-use asset       $ 300,000      
Lease term     18 months        
San Diego, CA - office space              
Lessee, Lease, Description [Line Items]              
Option to extend       true      
Renewal term       5 years      
Pasadena, CA - office and laboratory space              
Lessee, Lease, Description [Line Items]              
Addition of right-of-use asset       $ 15,300,000 $ 29,700,000    
Area of property | ft² 83,083   129,543        
Lease term 13 years            
Phases of lease term | phase     2        
Improvement allowance $ 17,000,000 $ 22,000,000          
Initial base monthly rent $ 386,336 $ 416,246          
Rent expense per square foot | uSDollarPerSquareFoot 4.65 5.01          
Rent increase (as a percentage) 3.00%            
Increase to tenant allowance   $ 5,000,000          
Forecast | Pasadena, CA - office and laboratory space              
Lessee, Lease, Description [Line Items]              
Area of property | ft²             46,460
Improvement allowance             $ 3,300,000