Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 53,942	$ 143,480
Marketable debt securities	526,689	153,767
Marketable equity securities	42,431	36,860
Accounts receivable	28,997	66,384
Prepaid expenses and other current assets	23,283	23,877
Total current assets	675,342	424,368
Property and equipment, net	59,183	28,240
Patents, licenses, and other intangible assets, net	18,500	16,493
Marketable debt securities - long term	3,826	300,465
Equity securities	54,383	31,262
Notes receivable - long term	0	5,000
Right of use asset	34,419	31,730
Other assets	613	653
Total assets	846,266	838,211
Current liabilities
Accounts payable	10,088	14,001
Accrued expenses	18,728	19,443
Lease liabilities	4,708	0
Deferred revenue	30,320	37,294
Total current liabilities	63,844	70,738
Lease liabilities, net of current portion	54,926	33,969
Total liabilities	118,770	104,707
Commitments and contingencies (see note 9)
Stockholders’ equity
Preferred stock, $0.01 par value: 10,000,000 authorized shares; -0- issued and outstanding shares at December 31, 2022 and 2021	0	0
Common stock, $0.01 par value: 200,000,000 authorized shares; 59,997,713 issued and outstanding shares at December 31, 2022 and 59,355,558 issued and outstanding at December 31, 2021	601	595
Additional paid-in capital	1,072,132	1,017,523
Accumulated other comprehensive income	(6,952)	(1,510)
Accumulated deficit	(338,285)	(283,104)
Total stockholders’ equity	727,496	733,504
Total liabilities and stockholders’ equity	$ 846,266	$ 838,211