Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets
Cash and cash equivalents	$ 52,654	$ 143,480
Marketable debt securities	515,398	153,767
Marketable equity securities	32,184	36,860
Accounts receivable	44,876	66,384
Prepaid expenses	22,886	23,877
Total current assets	667,998	424,368
Property and equipment, net	51,040	28,240
Patents, licenses, and other intangible assets, net	18,094	16,493
Marketable debt securities - long term	41,720	300,465
Marketable equity securities - long term	31,124	31,262
Notes receivable - long term	5,000	5,000
Right of use (ROU) asset	19,680	31,730
Other assets	613	653
Total assets	835,269	838,211
Current liabilities
Accounts payable	14,618	14,001
Accrued expenses	19,289	19,443
Lease liabilities	20,551
Deferred revenue	35,186	37,294
Income tax payable	388
Total current liabilities	90,032	70,738
Lease liabilities, net of current portion	22,539	33,969
Total liabilities	112,571	104,707
Commitments and contingencies
Stockholders' equity
Preferred stock, $0.01 par value: 10,000,000 authorized shares; -0- issued and outstanding shares at September 30, 2022 and December 31, 2021
Common stock, $0.01 par value: 200,000,000 authorized shares at September 30, 2022 and December 31, 2021; 59,773,337 issued and outstanding at September 30, 2022 and 59,355,558 issued and outstanding at December 31, 2021	598	595
Additional paid-in capital	1,058,219	1,017,523
Accumulated other comprehensive loss	(9,875)	(1,510)
Accumulated deficit	(326,244)	(283,104)
Total stockholders' equity	722,698	733,504
Total liabilities and stockholders' equity	$ 835,269	$ 838,211