Collaborative and Licensing Agreements - Revenue Recognition (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	$ 30,175	$ 67,447	$ 115,670	$ 101,412
Deferred revenue	35,300	19,200	35,300	19,200
Research collaboration
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	200	58,600	2,000	73,400
Milestone
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded		1,500	5,000	14,000
Royalties
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	30,000	7,300	108,700	14,000
Alexion Pharmaceuticals, Inc.
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	6,700	5,200	12,900	10,500
Astellas
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded			5,000
Genentech
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded		2,300		2,500
Janssen
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	200	16,200	2,000	30,800
MorphoSys
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	1,200	1,200	3,500	15,100
Novartis
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded		41,100		41,100
Vir
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Revenue recorded	$ 22,100	$ 1,400	$ 92,300	$ 1,400