XML 62 R52.htm IDEA: XBRL DOCUMENT v3.25.0.1
Collaboration and Licensing Agreements - Narrative (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Dec. 22, 2023
USD ($)
Oct. 01, 2021
Sep. 30, 2024
USD ($)
Jul. 31, 2024
USD ($)
Oct. 31, 2021
USD ($)
Feb. 28, 2019
USD ($)
Jan. 31, 2013
program
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2019
target
Dec. 31, 2023
USD ($)
Collaboration research and licensing agreements                          
Receivable     $ 25,872,000         $ 25,872,000   $ 25,872,000     $ 23,739,000
Collaborations, milestones, and royalties               17,796,000 $ 59,164,000 57,700,000 $ 123,649,000    
Impairment on equity securities               0 0 20,430,000 0    
Deferred revenue     0         0 9,200,000 0 9,200,000    
Royalties                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 14,500,000 100,000 41,500,000    
Milestone                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 46,000,000.0 500,000 61,000,000.0    
Alexion                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               15,700,000 31,800,000 42,100,000 53,400,000    
Gilead                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 6,000,000.0 0 6,000,000    
Omeros                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 5,000,000.0 0 5,000,000.0    
Mabgeek                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 0 1,500,000 0    
Vir                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 0 100,000 1,500,000    
Zenas                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 0 0 10,000,000.0    
Zenas | Preferred Stock                          
Collaboration research and licensing agreements                          
Equity shares estimated fair value     0         0   0     64,210,000
Third Party Licensee                          
Collaboration research and licensing agreements                          
Collaborations, milestones, and royalties               0 0 7,000,000.0 0    
Option and License agreement | Alexion                          
Collaboration research and licensing agreements                          
Number of different target programs | program             1            
Receivable     15,700,000         15,700,000   15,700,000      
Deferred revenue     0         0   0      
Option and License agreement | Alexion | Royalties                          
Collaboration research and licensing agreements                          
Revenue recognized               15,700,000 11,800,000 42,100,000 33,400,000    
Collaboration and License Agreement | Genentech                          
Collaboration research and licensing agreements                          
Revenue recognized               0 0 0 0    
Initial cost-sharing percentage           45.00%              
Royalty milestones           $ 600,000,000              
Collaboration and License Agreement | Genentech | Development-based                          
Collaboration research and licensing agreements                          
Royalty milestones           115,000,000              
Collaboration and License Agreement | Genentech | Regulatory-based                          
Collaboration research and licensing agreements                          
Royalty milestones           185,000,000              
Collaboration and License Agreement | Genentech | Sales-based                          
Collaboration research and licensing agreements                          
Royalty milestones           $ 300,000,000              
Collaboration and License Agreement | Genentech | XmAb24306                          
Collaboration research and licensing agreements                          
Collaborative arrangement receivable (payable) related to cost sharing development activities     (7,600,000)         (7,600,000)   (7,600,000)      
Collaboration and License Agreement | Genentech | Research service                          
Collaboration research and licensing agreements                          
Deferred revenue     0         0   0      
Collaboration and License Agreement | Janssen                          
Collaboration research and licensing agreements                          
Revenue recognized               0 7,500,000 0 7,500,000    
Deferred revenue     0         0   0      
Collaboration and License Agreement | MorphoSys/Incyte                          
Collaboration research and licensing agreements                          
Deferred revenue     0         0   0      
Collaboration and License Agreement | MorphoSys/Incyte | Royalties                          
Collaboration research and licensing agreements                          
Revenue recognized               2,100,000 2,700,000 6,500,000 6,600,000    
Receivable     2,100,000         2,100,000   2,100,000      
Second Collaboration And License Agreement | Janssen                          
Collaboration research and licensing agreements                          
Revenue recognized               0 6,200,000 0 33,600,000    
Receivable     2,300,000         2,300,000   2,300,000      
Deferred revenue     0         0   0      
Research license term   2 years                      
Second Collaboration And License Agreement | Janssen | Maximum                          
Collaboration research and licensing agreements                          
Percentage of responsibility for development costs   20.00%                      
Second Collaboration And License Agreement | Janssen | Minimum                          
Collaboration research and licensing agreements                          
Share development percentage   80.00%                      
Technology License Agreement | Mabgeek                          
Collaboration research and licensing agreements                          
Deferred revenue     0         0   0      
Collaborations, milestones, and royalties               0   1,500,000      
Collaborative arrangement nonrefundable upfront fees $ 1,500,000                        
Royalty milestones $ 11,900,000                        
Technology License Agreement | Vega                          
Collaboration research and licensing agreements                          
Revenue recognized         $ 500,000                
Collaborations, milestones, and royalties               0 0 500,000 0    
Technology License Agreement | Gale                          
Collaboration research and licensing agreements                          
Transaction price     7,500,000         7,500,000   7,500,000      
Service agreement charges               2,700,000   10,700,000      
Payments for repurchase of preferred stock and preference stock     3,000,000.0 $ 3,000,000.0       6,000,000.0          
License | Zenas                          
Collaboration research and licensing agreements                          
Revenue recognized               0 0 0 10,000,000.0    
Deferred revenue                 $ 0   0    
License | Zenas | Milestone | Preferred Stock                          
Collaboration research and licensing agreements                          
Equity shares estimated fair value                         $ 10,000,000.0
Patent License Agreement | Vir                          
Collaboration research and licensing agreements                          
Number of different target programs | target                       2  
Receivable     0         0   0      
Deferred revenue     0         0   0      
Patent License Agreement | Vir | Royalties                          
Collaboration research and licensing agreements                          
Revenue recognized                   100,000 $ 1,500,000    
Patent License Agreement | Third Party Licensee                          
Collaboration research and licensing agreements                          
Receivable     0         0   0      
Deferred revenue     $ 0         0   0      
Collaborations, milestones, and royalties               $ 0   $ 7,000,000.0