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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 HjzGDFLA25xy9cDFki7aBw/ySc3+djfXm2V+C+Hks9pF4Va6kjOWLQhaSbJ9Uw7t
 q6/TpsCH9lii0+NNhtw3nw==

<SEC-DOCUMENT>0001104659-10-051014.txt : 20101004
<SEC-HEADER>0001104659-10-051014.hdr.sgml : 20101004
<ACCEPTANCE-DATETIME>20101004093319
ACCESSION NUMBER:		0001104659-10-051014
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20101001
FILED AS OF DATE:		20101004
DATE AS OF CHANGE:		20101004

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Frishberg Brad
		CENTRAL INDEX KEY:			0001492644

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	811-21765
		FILM NUMBER:		101104156

	MAIL ADDRESS:	
		STREET 1:		125 WEST 55TH STREET
		STREET 2:		LEVEL 10
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Macquarie Global Infrastructure Total Return Fund Inc.
		CENTRAL INDEX KEY:			0001326390
		IRS NUMBER:				342045907

	BUSINESS ADDRESS:	
		STREET 1:		C/O MACQUARIE  FUND ADVISER, LLC
		STREET 2:		125 WEST 55TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		212-231-1572

	MAIL ADDRESS:	
		STREET 1:		C/O MACQUARIE  FUND ADVISER, LLC
		STREET 2:		125 WEST 55TH STREET
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>a4.xml
<DESCRIPTION>4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-10-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001326390</issuerCik>
        <issuerName>Macquarie Global Infrastructure Total Return Fund Inc.</issuerName>
        <issuerTradingSymbol>MGU</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001492644</rptOwnerCik>
            <rptOwnerName>Frishberg Brad</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O MACQUARIE CAPITAL INVESTMENT MANAGEM</rptOwnerStreet1>
            <rptOwnerStreet2>125 W. 55TH ST., 10TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>MGU Common Shares</value>
            </securityTitle>
            <transactionDate>
                <value>2010-10-01</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2010-10-01</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>6000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>16.63</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Brad Frishberg</signatureName>
        <signatureDate>2010-10-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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