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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (49,044,477) $ (20,520,131)
Adjustments to reconcile net loss to net cash used in operating activities:    
Non-cash consideration for acquired in-process research and development   6,541,485
Changes in fair value of contingent consideration liability 16,265,010  
Impairment charge 0 1,000,000
Stock-based compensation expense 2,576,006 1,264,231
Depreciation and amortization 298,057 387,321
Unrealized gain on foreign currency exchange (19,073) (5,761)
Changes in fair value of warrant liability   (30,000)
Changes in operating assets and liabilities:    
Accounts receivable (3,589,024) 2,440,759
Prepaid expenses and other current assets (1,371,312) 133,001
Accounts payable 594,060 (354,628)
Accrued expenses and other liabilities 6,987,815 (779,651)
Tax refund receivable (7,133,698) 379,877
Deferred taxes   (58,500)
Net cash used in operating activities (34,436,636) (9,601,997)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Proceeds from sales and maturities of short-term investments 56,406,564  
Purchases of short-term investments (128,159,098) (28,257,379)
Purchases of property and equipment (203,957) (1,227)
Cash paid for internally developed patents (138,464) (27,772)
Net cash used in investing activities (72,094,955) (28,286,378)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Cash paid in conjunction with warrant exchange   (25,000)
Proceeds from exercises of warrants 41,038,458 30,324
Proceeds from issuance of common stock in at-the-market offering, net 48,156,072  
Proceeds from issuance of common stock and pre-funded warrants in public offering, net 124,027,815  
Proceeds from issuance of common stock in registered direct offering, net   12,668,784
Proceeds from issuance of notes payable 632,000  
Payments of notes payable (632,000) (292,002)
Proceeds from conditional economic incentive   150,000
Proceeds from issuance of common stock from Employee Stock Purchase Plan 135,471  
Proceeds from exercises of stock options 128,896  
Net cash provided by financing activities 213,486,712 12,532,106
Net increase (decrease) in cash, cash equivalents and restricted cash 106,955,121 (25,356,269)
Cash, cash equivalents and restricted cash — beginning of year 8,996,860 34,353,129
Cash, cash equivalents and restricted cash — end of year 115,951,981 8,996,860
SUPPLEMENTAL NON-CASH ACTIVITIES:    
Common stock issued related to contingent consideration liability 13,625,010  
Common stock issued for acquired in-process research and development   3,791,485
Operating lease liability and right of use asset addition $ 338,212 $ 1,744,128