Consolidated Statements of changes in Stockholders' Equity - USD ($)	Total	Market Offering [Member]	Registered Direct Offering [Member]	Common Stock [Member]	Common Stock [Member] Market Offering [Member]	Common Stock [Member] Registered Direct Offering [Member]	Additional Paid-In Capital [Member]	Additional Paid-In Capital [Member] Market Offering [Member]	Additional Paid-In Capital [Member] Registered Direct Offering [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]
Beginning Balance at Dec. 31, 2018	$ 48,312,566			$ 876			$ 170,207,844			$ (116,855,991)	$ (5,040,163)
Beginning Balance (in shares) at Dec. 31, 2018				9,078,238
Stock based compensation	1,264,231						1,264,231
Vesting of restricted stock awards including withholding, net	(47,120)			$ 6			(47,126)
Vesting of restricted stock awards including withholding, net (in shares)				(25,691)
Issuance of common stock, net			$ 12,668,784			$ 436			$ 12,668,348
Issuance of common stock, net (in shares)						4,361,370
Issuance of common stock for contingent consideration liability	3,791,485			$ 189			3,791,296
Issuance of common stock for contingent consideration liability (in shares)				1,887,250
Issuance of common stock upon exercise of warrants	30,324			$ 1			30,323
Issuance of common stock upon exercise of warrants (in shares)				11,000
Unrealized (loss) gain on short-term investments	20,007										20,007
Net loss	(20,520,131)									(20,520,131)
Ending Balance at Dec. 31, 2019	45,520,146			$ 1,508			187,914,916			(137,376,122)	(5,020,156)
Ending Balance (in shares) at Dec. 31, 2019				15,312,167
Stock based compensation	2,576,006						2,576,006
Issuance of common stock from exercise of stock options	$ 128,896			$ 4			128,892
Issuance of common stock from exercise of stock options (in shares)	46,966			46,966
Vesting of restricted stock awards including withholding, net	$ (262,713)			$ 16			(262,729)
Vesting of restricted stock awards including withholding, net (in shares)				84,320
Issuance of common stock from Employee Stock Purchase Plan	135,471			$ 8			135,463
Issuance of common stock from Employee Stock Purchase Plan (in shares)				92,661
Issuance of common stock and pre-funded warrants in public offering, net	124,027,815			$ 412			124,027,403
Issuance of common stock and pre-funded warrants in public offering, net (in shares)				4,119,564
Issuance of common stock, net		$ 48,156,072			$ 560			$ 48,155,512
Issuance of common stock, net (in shares)					5,594,455
Issuance of common stock for contingent consideration liability	13,625,010			$ 169			13,624,841
Issuance of common stock for contingent consideration liability (in shares)				1,694,906
Issuance of common stock upon exercise of warrants	41,038,458			$ 1,020			41,037,438
Issuance of common stock upon exercise of warrants (in shares)				10,197,907
Unrealized (loss) gain on short-term investments	(24,361)										(24,361)
Net loss	(49,044,477)									(49,044,477)
Ending Balance at Dec. 31, 2020	$ 225,876,323			$ 3,697			$ 417,337,742			$ (186,420,599)	$ (5,044,517)
Ending Balance (in shares) at Dec. 31, 2020				37,142,946