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Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (38,422,700) $ (16,423,506)
Adjustments to reconcile net loss to net cash used in operating activities:    
Non-cash consideration for acquired in-process research and development   6,541,485
Change in fair value of contingent consideration liability 22,320,000  
Impairment charge   1,000,000
Stock-based compensation expense 1,865,520 985,260
Depreciation 182,650 181,314
Amortization 36,282 135,664
Unrealized gains on foreign currency exchange (44,323) (3,310)
Changes in fair value of warrant liability   (30,000)
Changes in operating assets and liabilities:    
Accounts receivable (2,815,343) 2,449,447
Prepaid expenses and other current assets (636,943) 179,298
Accounts payable 856,653 (322,976)
Accrued expenses and other liabilities 1,199,708 (2,274,497)
Tax refund receivable (5,564,759) 40,376
Deferred taxes   (58,500)
Net cash used in operating activities (21,023,255) (7,599,945)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Proceeds from sales and maturities of short-term investments 39,385,689  
Purchases of short-term investments (74,413,135) (28,207,073)
Purchase of property and equipment (100,329) (1,227)
Cash paid for internally developed patents (98,893) (25,396)
Net cash used in investing activities (35,226,668) (28,233,696)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Cash paid in conjunction with warrant exchange   (25,000)
Payments of deferred offering costs (160,522)  
Proceeds from exercises of warrants 41,038,458 30,324
Proceeds from issuance of common stock in at the market offering, net 25,614,836  
Proceeds from issuance of common stock and pre-funded warrants in public offering, net 124,027,815  
Proceeds from issuance of common stock in registered direct offering, net   12,668,784
Proceeds from issuance of notes payable 632,000  
Payments of notes payable (632,000) (186,940)
Proceeds from issuance of common stock from Employee Stock Purchase Plan 135,471  
Proceeds from exercises of stock options 126,445  
Net cash provided by financing activities 190,782,503 12,487,168
Net increase and decrease in cash and cash equivalents and restricted cash 134,532,580 (23,346,473)
Cash, cash equivalents and restricted cash at beginning of period 8,996,860 34,353,129
Cash, cash equivalents and restricted cash at end of period 143,529,440 11,006,656
SUPPLEMENTAL CASH FLOW INFORMATION:    
Cash paid for interest $ 1,791  
SUPPLEMENTAL NON-CASH FINANCING ACTIVITIES:    
Common stock issued for acquired in-process research and development   $ 3,791,485