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Consolidated Statements of changes in Stockholders' Equity - USD ($)
Total
Market Offering [Member]
Registered Direct Offering [Member]
Common Stock [Member]
Common Stock [Member]
Market Offering [Member]
Common Stock [Member]
Registered Direct Offering [Member]
Additional Paid-In Capital [Member]
Additional Paid-In Capital [Member]
Market Offering [Member]
Additional Paid-In Capital [Member]
Registered Direct Offering [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Loss [Member]
Beginning Balance at Dec. 31, 2018 $ 48,312,566     $ 876     $ 170,207,844     $ (116,855,991) $ (5,040,163)
Beginning Balance (in shares) at Dec. 31, 2018       9,078,238              
Stock-based compensation 407,714           407,714        
Vesting of restricted stock awards including withholding, net 28           28        
Vesting of restricted stock awards including withholding, net (in shares)       71              
Issuance of common stock, net     $ 12,668,784     $ 436     $ 12,668,348    
Issuance of common stock, net (in shares)           4,361,370          
Issuance of common stock upon exercise of warrants 30,324     $ 1     30,323        
Issuance of common stock upon exercise of warrants (in shares)       11,000              
Net loss (2,097,306)                 (2,097,306)  
Ending Balance at Mar. 31, 2019 59,322,110     $ 1,313     183,314,257     (118,953,297) (5,040,163)
Ending Balance (in shares) at Mar. 31, 2019       13,450,679              
Beginning Balance at Dec. 31, 2018 48,312,566     $ 876     170,207,844     (116,855,991) (5,040,163)
Beginning Balance (in shares) at Dec. 31, 2018       9,078,238              
Unrealized (loss) gain on short-term investments 18,953                    
Net loss (16,423,506)                    
Ending Balance at Sep. 30, 2019 49,383,950     $ 1,502     187,683,155     (133,279,497) (5,021,210)
Ending Balance (in shares) at Sep. 30, 2019       15,338,072              
Beginning Balance at Mar. 31, 2019 59,322,110     $ 1,313     183,314,257     (118,953,297) (5,040,163)
Beginning Balance (in shares) at Mar. 31, 2019       13,450,679              
Stock-based compensation 289,772           289,772        
Vesting of restricted stock awards including withholding, net 28           28        
Vesting of restricted stock awards including withholding, net (in shares)       71              
Net loss (3,386,888)                 (3,386,888)  
Ending Balance at Jun. 30, 2019 56,225,022     $ 1,313     183,604,057     (122,340,185) (5,040,163)
Ending Balance (in shares) at Jun. 30, 2019       13,450,750              
Stock-based compensation 287,774           287,774        
Vesting of restricted stock awards including withholding, net 28           28        
Vesting of restricted stock awards including withholding, net (in shares)       72              
Issuance of common stock for acquired in-process research and development 3,791,485     $ 189     3,791,296        
Issuance of common stock for acquired in-process research and development (in shares)       1,887,250              
Unrealized (loss) gain on short-term investments 18,953                   18,953
Net loss (10,939,312)                 (10,939,312)  
Ending Balance at Sep. 30, 2019 49,383,950     $ 1,502     187,683,155     (133,279,497) (5,021,210)
Ending Balance (in shares) at Sep. 30, 2019       15,338,072              
Beginning Balance at Dec. 31, 2019 45,520,146     $ 1,508     187,914,916     (137,376,122) (5,020,156)
Beginning Balance (in shares) at Dec. 31, 2019       15,312,167              
Stock-based compensation 214,921           214,921        
Vesting of restricted stock awards including withholding, net (17,079)     $ 1     (17,080)        
Vesting of restricted stock awards including withholding, net (in shares)       (5,974)              
Issuance of common stock from Employee Stock Purchase Plan 56,739     $ 3     56,736        
Issuance of common stock from Employee Stock Purchase Plan (in shares)       38,809              
Issuance of common stock upon exercise of warrants 39,974     $ 2     39,972        
Issuance of common stock upon exercise of warrants (in shares)       14,500              
Unrealized (loss) gain on short-term investments (32,435)                   (32,435)
Net loss (3,885,649)                 (3,885,649)  
Ending Balance at Mar. 31, 2020 41,896,617     $ 1,514     188,209,465     (141,261,771) (5,052,591)
Ending Balance (in shares) at Mar. 31, 2020       15,359,502              
Beginning Balance at Dec. 31, 2019 45,520,146     $ 1,508     187,914,916     (137,376,122) (5,020,156)
Beginning Balance (in shares) at Dec. 31, 2019       15,312,167              
Unrealized (loss) gain on short-term investments (22,116)                    
Net loss (38,422,700)                    
Ending Balance at Sep. 30, 2020 199,705,835     $ 3,289     380,543,640     (175,798,822) (5,042,272)
Ending Balance (in shares) at Sep. 30, 2020       33,073,035              
Beginning Balance at Mar. 31, 2020 41,896,617     $ 1,514     188,209,465     (141,261,771) (5,052,591)
Beginning Balance (in shares) at Mar. 31, 2020       15,359,502              
Stock-based compensation 330,510           330,510        
Issuance of common stock from exercise of stock options 36,175     $ 1     36,174        
Issuance of common stock from exercise of stock options (in shares)       13,935              
Vesting of restricted stock awards including withholding, net (46,389)     $ 1     (46,390)        
Vesting of restricted stock awards including withholding, net (in shares)       (5,974)              
Issuance of common stock, net   $ 22,780,729     $ 297     $ 22,780,432      
Issuance of common stock, net (in shares)         2,965,144            
Issuance of common stock upon exercise of warrants 31,270,163     $ 822     31,269,341        
Issuance of common stock upon exercise of warrants (in shares)       8,221,279              
Unrealized (loss) gain on short-term investments 20,888                   20,888
Net loss (16,766,916)                 (16,766,916)  
Ending Balance at Jun. 30, 2020 79,521,777     $ 2,635     242,579,532     (158,028,687) (5,031,703)
Ending Balance (in shares) at Jun. 30, 2020       26,553,886              
Stock-based compensation 1,320,089           1,320,089        
Issuance of common stock from exercise of stock options 90,270     $ 3     90,267        
Issuance of common stock from exercise of stock options (in shares)       32,189              
Vesting of restricted stock awards including withholding, net (114,572)     $ 13     (114,585)        
Vesting of restricted stock awards including withholding, net (in shares)       103,551              
Issuance of common stock from Employee Stock Purchase Plan 78,732     $ 5     78,727        
Issuance of common stock from Employee Stock Purchase Plan (in shares)       53,852              
Issuance of common stock and pre-funded warrants in public offering, net 124,027,815     $ 412     124,027,403        
Issuance of common stock and pre-funded warrants in public offering, net (in shares)       4,119,564              
Issuance of common stock, net   $ 2,834,107     $ 25     $ 2,834,082      
Issuance of common stock, net (in shares)         247,865            
Issuance of common stock upon exercise of warrants 9,728,321     $ 196     9,728,125        
Issuance of common stock upon exercise of warrants (in shares)       1,962,128              
Unrealized (loss) gain on short-term investments (10,569)                   (10,569)
Net loss (17,770,135)                 (17,770,135)  
Ending Balance at Sep. 30, 2020 $ 199,705,835     $ 3,289     $ 380,543,640     $ (175,798,822) $ (5,042,272)
Ending Balance (in shares) at Sep. 30, 2020       33,073,035