Goodwill and Intangible Assets - Schedule of Intangible Assets (Detail) - USD ($)	6 Months Ended	12 Months Ended
	Jun. 30, 2019	Dec. 31, 2018
Schedule Of Intangible Assets [Line Items]
Intangible assets subject to amortization, Gross Carrying Value	$ 1,019,432	$ 1,003,559
Intangible assets subject to amortization, Accumulated Amortization	(678,183)	(570,602)
Intangible assets subject to amortization, Net Book Value	341,249	432,957
Total intangible assets, Gross Carrying Value	14,438,399	38,872,537
Intangible Assets, Impairment		24,450,011
Total intangible assets, Net Book Value	13,760,216	13,851,924
Intangible Assets, Impairment		(24,450,011)
IPR&D [Member]
Schedule Of Intangible Assets [Line Items]
Total intangible assets, Gross Carrying Value	13,418,967	37,868,978
Total intrangible assets, Impairment		(24,450,011)
Total intangible assets, Net Book Value	13,418,967	13,418,967
Internally Developed Patents [Member]
Schedule Of Intangible Assets [Line Items]
Intangible assets subject to amortization, Gross Carrying Value	734,432	718,559
Intangible assets subject to amortization, Accumulated Amortization	(416,857)	(317,172)
Intangible assets subject to amortization, Net Book Value	$ 317,575	$ 401,387
Internally Developed Patents [Member] | Minimum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	6 years	6 years
Internally Developed Patents [Member] | Maximum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	10 years	10 years
Acquired Licenses [Member]
Schedule Of Intangible Assets [Line Items]
Intangible assets subject to amortization, Gross Carrying Value	$ 285,000	$ 285,000
Intangible assets subject to amortization, Accumulated Amortization	(261,326)	(253,430)
Intangible assets subject to amortization, Net Book Value	$ 23,674	$ 31,570
Acquired Licenses [Member] | Minimum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	16 years	16 years
Acquired Licenses [Member] | Maximum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	20 years	20 years