Intangible Assets, Net and Goodwill (Tables)

12 Months Ended

Dec. 31, 2018

Goodwill And Intangible Assets Disclosure [Abstract]

Schedule of Intangible Assets

The Company’s intangible assets consisted of the following:

	As of December 31, 2018
	Estimated Useful Lives	Gross Carrying Value		Accumulated Amortization			Impairment			Net Book Value
Internally developed patents	6 – 10 years	$	718,559	$	(317,172	)	$	—		$	401,387
Acquired licenses	16 – 20 years		285,000		(253,430	)		—			31,570
Total intangible assets subject to amortization		$	1,003,559	$	(570,602	)	$	—		$	432,957
IPR&D assets	Indefinite		37,868,978		—			(24,450,011	)		13,418,967
Total		$	38,872,537	$	(570,602	)	$	(24,450,011	)	$	13,851,924

	December 31, 2017
	Estimated Useful Lives	Gross Carrying Value		Accumulated Amortization			Net Book Value
Internally developed patents	6 – 10 years	$	678,340	$	(249,601	)	$	428,739
Acquired licenses	16 – 20 years		285,000		(237,340	)		47,660
Total intangible assets subject to amortization		$	963,340	$	(486,941	)	$	476,399
IPR&D assets	Indefinite		38,245,871		—			38,245,871
Total		$	39,209,211	$	(486,941	)	$	38,722,270

Schedule of Future Estimated Amortization Expense

As of December 31, 2018, future estimated amortization expense is as follows:

For the Year Ended December 31,
2019	$	59,377
2020		45,930
2021		25,371
2022		25,371
2023		25,371
2024 and thereafter		251,537
Total	$	432,957

Schedule of Changes in Carrying Amounts of IPR&D Assets and Goodwill

Changes in the carrying amounts of IPR&D assets and goodwill for the years ended December 31, 2018 and 2017 were:

	IPR&D			Goodwill
Balance, January 1, 2017	$	14,477,019		$	18,758,421
Additions from the Mergers		22,389,000			15,573,822
Foreign currency translation adjustments		1,379,852			1,587,452
Impairment charges		—			(35,919,695	)
Balance, December 31, 2017	$	38,245,871		$	—
Additions		—			490,676
Foreign currency translation adjustments		(376,893	)		—
Impairment charges		(24,450,011	)		(490,676	)
Balance, December 31, 2018	$	13,418,967		$	—