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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (19,430) $ (14,864)
Adjustments to reconcile net loss to net cash used in operating activities:    
Change in fair value of contingent consideration liability (1,780) 880
Stock-based compensation expense 2,033 1,218
Depreciation and amortization 119 74
Unrealized (gains) losses on foreign currency exchange (110) 33
Changes in operating assets and liabilities:    
Accounts receivable 236 (191)
Prepaid expenses and other current assets 3,046 (4,201)
Accounts payable 171 (194)
Accrued expenses and other liabilities 2,659 (2,189)
Income tax and R&D incentive receivables (470) (135)
Net cash used in operating activities (13,526) (19,569)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Proceeds from sales and maturities of short-term investments   30,912
Purchases of short-term investments   (7,476)
Purchases of property and equipment, net (9) (4,209)
Cash paid for internally developed patents   (62)
Net cash (used in) provided by investing activities (9) 19,165
CASH FLOWS FROM FINANCING ACTIVITIES:    
Payments of deferred offering costs (119) 135
Proceeds from issuance of common stock in at-the-market offerings, net 2,990 34,178
Proceeds from issuance of common stock from Employee Stock Purchase Plan 113 106
Proceeds from exercises of stock options 197  
Net cash provided by financing activities 3,181 34,419
Net (decrease) increase in cash and cash equivalents and restricted cash (10,354) 34,015
Cash, cash equivalents and restricted cash at beginning of period 190,335 115,952
Cash, cash equivalents and restricted cash at end of period $ 179,981 149,967
SUPPLEMENTAL NON-CASH ACTIVITIES:    
Fair value of common stock retired in exchange for issuance of common stock warrant   $ 17,200