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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (97,090,824) $ (49,044,477)
Adjustments to reconcile net loss to net cash used in operating activities:    
Change in fair value of contingent consideration liability 700,000 16,265,010
Impairment loss on construction-in-progress 11,370,000  
Impairment loss on intangible assets 579,497  
Stock-based compensation expense 5,518,890 2,576,006
Depreciation and amortization 551,301 428,878
Unrealized losses (gains) on foreign currency exchange 383,721 (19,073)
Changes in operating assets and liabilities:    
Accounts receivable 4,181,366 (3,589,024)
Prepaid expenses and other current assets (5,907,878) (1,371,312)
Accounts payable 1,422,200 594,060
Accrued expenses and other liabilities (2,299,368) 6,987,815
Income tax and R&D incentive receivables 2,353,154 (7,133,698)
Net cash used in operating activities (78,237,941) (34,305,815)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Proceeds from sales and maturities of short-term investments 107,426,876 56,406,564
Purchases of short-term investments (7,592,100) (128,289,919)
Purchases of property and equipment, net (12,117,111) (203,957)
Cash paid for internally developed patents (194,538) (138,464)
Net cash provided by (used in) investing activities 87,523,127 (72,225,776)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Payments of deferred offering costs (118,522)  
Proceeds from exercises of warrants   41,038,458
Proceeds from issuance of common stock in at-the-market offerings, net 64,815,379 48,156,072
Proceeds from issuance of common stock and pre-funded warrants in public offering, net   124,027,815
Proceeds from issuance of notes payable   632,000
Payments of notes payable   (632,000)
Proceeds from issuance of common stock from Employee Stock Purchase Plan 224,472 135,471
Proceeds from exercises of stock options 176,454 128,896
Net cash provided by financing activities 65,097,783 213,486,712
Net increase in cash and cash equivalents and restricted cash 74,382,969 106,955,121
Cash, cash equivalents and restricted cash at beginning of period 115,951,981 8,996,860
Cash, cash equivalents and restricted cash at end of period 190,334,950 115,951,981
SUPPLEMENTAL CASH FLOW INFORMATION:    
Cash paid for interest   1,791
SUPPLEMENTAL NON-CASH ACTIVITIES:    
Common stock issued related to contingent consideration liability 17,200,000 13,625,010
Operating lease liability and right of use asset addition $ 72,047 $ 338,212