Consolidated Statements of changes in Stockholders' Equity - USD ($)	Common Stock [Member] Market Offering [Member]	Common Stock [Member]	Additional Paid-In Capital [Member] Market Offering [Member]	Additional Paid-In Capital [Member]	Accumulated Deficit [Member]	Accumulated Other Comprehensive Loss [Member]	Market Offering [Member]	Total
Beginning Balance at Dec. 31, 2019		$ 1,508		$ 187,914,916	$ (137,376,122)	$ (5,020,156)		$ 45,520,146
Beginning Balance (in shares) at Dec. 31, 2019		15,312,167
Stock-based compensation				2,576,006				2,576,006
Exercise of stock options		$ 4		128,892				128,896
Exercise of stock options (in shares)		46,966
Vesting of restricted stock awards including withholding, net		$ 16		(262,729)				(262,713)
Vesting of restricted stock awards including withholding, net (in shares)		84,320
Issuance of common stock from Employee Stock Purchase Plan		$ 8		135,463				135,471
Issuance of common stock from Employee Stock Purchase Plan (in shares)		92,661
Issuance of common stock and pre-funded warrants in public offering, net		$ 412		124,027,403				124,027,815
Issuance of common stock and pre-funded warrants in public offering, net (in shares)		4,119,564
Issuance of common stock in at the market offerings, net	$ 560		$ 48,155,512				$ 48,156,072
Issuance of common stock in at the market offerings, net (in shares)	5,594,455
Issuance of common stock related to contingent consideration liability		$ 169		13,624,841				13,625,010
Issuance of common stock related to contingent consideration liability (in shares)		1,694,906
Issuance of common stock upon cashless exercise of warrants		$ 1,020		41,037,438				41,038,458
Issuance of common stock upon cashless exercise of warrants (in shares)		10,197,907
Unrealized (loss) gain on short-term investments						(24,361)		(24,361)
Net loss					(49,044,477)			(49,044,477)
Ending Balance at Dec. 31, 2020		$ 3,697		417,337,742	(186,420,599)	(5,044,517)		225,876,323
Ending Balance (in shares) at Dec. 31, 2020		37,142,946
Stock-based compensation				5,518,890				5,518,890
Exercise of stock options		$ 6		176,448				$ 176,454
Exercise of stock options (in shares)		54,068						54,068
Vesting of restricted stock awards including withholding, net		$ 4		(400,341)				$ (400,337)
Vesting of restricted stock awards including withholding, net (in shares)		(28,850)
Issuance of common stock from Employee Stock Purchase Plan		$ 3		224,469				224,472
Issuance of common stock from Employee Stock Purchase Plan (in shares)		24,100
Retirement of common stock in exchange for common stock warrant		$ (100)		(7,539,900)	(9,660,000)			(17,200,000)
Retirement of common stock in exchange for common stock warrant (in Shares)		(1,000,000)
Issuance Of Common Stock Warrant In Exchange For Retirement Of Common Stock				(17,200,000)				(17,200,000)
Issuance of common stock in at the market offerings, net	$ 480		$ 64,814,899				$ 64,815,379
Issuance of common stock in at the market offerings, net (in shares)	4,800,454
Issuance of common stock upon cashless exercise of warrants				10,000				10,000
Issuance of common stock upon cashless exercise of warrants (in shares)		1,050
Unrealized (loss) gain on short-term investments						4,354		4,354
Net loss					(97,090,824)			(97,090,824)
Ending Balance at Dec. 31, 2021		$ 4,090		$ 497,342,207	$ (293,171,423)	$ (5,040,163)		$ 199,134,711
Ending Balance (in shares) at Dec. 31, 2021		40,993,768