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Intangible Assets - Schedule of Intangible Assets (Detail) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Schedule Of Intangible Assets [Line Items]    
Intangible assets subject to amortization, Gross Carrying Value $ 1,364,325 $ 1,169,787
Intangible assets subject to amortization, Accumulated Amortization (784,828) (764,908)
Intangible assets subject to amortization, Net Book Value   404,879
Total intangible assets, Gross Carrying Value 13,783,292 13,588,754
Total intangible assets, Impairment (579,497)  
Intangible Assets, Impairment (579,497)  
Total intangible assets, Net Book Value 12,418,967 12,823,846
IPR&D [Member]    
Schedule Of Intangible Assets [Line Items]    
Total intangible assets, Gross Carrying Value 12,418,967 12,418,967
Total intangible assets, Net Book Value 12,418,967 12,418,967
Internally Developed Patents [Member]    
Schedule Of Intangible Assets [Line Items]    
Intangible assets subject to amortization, Gross Carrying Value 1,079,325 884,787
Intangible assets subject to amortization, Accumulated Amortization (499,828) (479,908)
Intangible assets subject to amortization, Net Book Value   $ 404,879
Intangible Assets, Impairment $ (579,497)  
Internally Developed Patents [Member] | Minimum [Member]    
Schedule Of Intangible Assets [Line Items]    
Estimated Useful Lives 6 years 6 years
Internally Developed Patents [Member] | Maximum [Member]    
Schedule Of Intangible Assets [Line Items]    
Estimated Useful Lives 20 years 10 years
Acquired Licenses [Member]    
Schedule Of Intangible Assets [Line Items]    
Intangible assets subject to amortization, Gross Carrying Value $ 285,000 $ 285,000
Intangible assets subject to amortization, Accumulated Amortization $ (285,000) $ (285,000)
Acquired Licenses [Member] | Minimum [Member]    
Schedule Of Intangible Assets [Line Items]    
Estimated Useful Lives 16 years 16 years
Acquired Licenses [Member] | Maximum [Member]    
Schedule Of Intangible Assets [Line Items]    
Estimated Useful Lives 20 years 20 years