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CONSOLIDATED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Deficit [Member]
Accumulated Other Comprehensive Loss [Member]
Total
Beginning Balance at Dec. 31, 2020 $ 4 $ 417,337 $ (186,421) $ (5,044) $ 225,876
Beginning Balance (in shares) at Dec. 31, 2020 37,142,946        
Stock-based compensation   5,519     5,519
Exercise of stock options   176     176
Exercise of stock options (in shares) 54,068        
Vesting of restricted stock awards including withholding, net   (400)     (400)
Vesting of restricted stock awards including withholding, net (in shares) (28,850)        
Issuance of common stock from Employee Stock Purchase Plan   225     225
Issuance of common stock from Employee Stock Purchase Plan (in shares) 24,100        
Retirement of common stock in exchange for common stock warrant   (7,540) (9,660)   (17,200)
Retirement of common stock in exchange for common stock warrant (in Shares) (1,000,000)        
Issuance of common stock warrant in exchange for retirement of common stock   17,200     17,200
Issuance of common stock in at the market offerings, net   64,815     64,815
Issuance of common stock in at the market offerings, net (in shares) 4,800,454        
Issuance of common stock upon cashless exercise of warrants   10     10
Issuance of common stock upon cashless exercise of warrants (in shares) 1,050        
Unrealized (loss) gain on short-term investments       4 4
Net loss     (97,090)   (97,090)
Ending Balance at Dec. 31, 2021 $ 4 497,342 (293,171) (5,040) 199,135
Ending Balance (in shares) at Dec. 31, 2021 40,993,768        
Stock-based compensation   8,101     8,101
Exercise of stock options   950     $ 950
Exercise of stock options (in shares) 358,317       373,545
Vesting of restricted stock awards including withholding, net   (516)     $ (516)
Vesting of restricted stock awards including withholding, net (in shares) 8,695        
Issuance of common stock from Employee Stock Purchase Plan   181     181
Issuance of common stock from Employee Stock Purchase Plan (in shares) 26,395        
Issuance of common stock in at the market offerings, net $ 1 56,165     56,166
Issuance of common stock in at the market offerings, net (in shares) 5,204,215        
Issuance of common stock related to contingent consideration liability   6,176     6,176
Issuance of common stock related to contingent consideration liability (in shares) 847,444        
Issuance of common stock upon cashless exercise of warrants (in shares) 1,760,854        
Other increase (in shares) 157        
Unrealized (loss) gain on short-term investments       (187) (187)
Net loss     (84,713)   (84,713)
Ending Balance at Dec. 31, 2022 $ 5 $ 568,399 $ (377,884) $ (5,227) $ 185,293
Ending Balance (in shares) at Dec. 31, 2022 49,199,845