Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expense and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Accrued Liabilities And Other Liabilities [Abstract]
Accrued professional services	$ 276	$ 396
Accrued payroll and employee benefits	2,955	2,313
Accrued research and development	7,295	6,988
Lease obligation, current portion (see Note 6)	$ 452	$ 411
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]	Total accrued expenses and other current liabilities	Total accrued expenses and other current liabilities
Excess tax refund payable	$ 1,169
Accrued interest and other	103	$ 44
Total accrued expenses and other current liabilities	$ 12,250	$ 10,152