Property and Equipment, Net - Summary of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Property Plant And Equipment [Line Items]
Property and equipment, at cost	$ 2,579	$ 3,495
Less: accumulated depreciation and amortization	(1,498)	(2,047)
Property and equipment, net	1,081	1,448
Furniture, Fixtures and Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, at cost	163	222
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, at cost	295	1,040
Computers and Telecommunications [Member]
Property Plant And Equipment [Line Items]
Property and equipment, at cost	194	291
Software [Member]
Property Plant And Equipment [Line Items]
Property and equipment, at cost	178	148
Leasehold Improvements
Property Plant And Equipment [Line Items]
Property and equipment, at cost	$ 1,749	$ 1,794