Accrued Expenses - Schedule of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Accrued Liabilities And Other Liabilities [Abstract]
Accrued professional services	$ 624	$ 396
Accrued payroll and employee benefits	2,110	2,313
Accrued research and development	9,930	6,988
Lease obligation, current portion (see Note 4)	442	411
Income tax payable	1,169
Accrued interest and other	48	44
Total accrued expenses and other current liabilities	$ 14,323	$ 10,152