-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 CPip+3DwQEjRqBKPsPPDnAcHjAGUBxDYa4D14zF5rI5JjeLguVurjjRnRiG6M64L
 6G9Lucz487xgNhmf53bEWQ==

<SEC-DOCUMENT>0001231919-07-000111.txt : 20071113
<SEC-HEADER>0001231919-07-000111.hdr.sgml : 20071112
<ACCEPTANCE-DATETIME>20071113145226
ACCESSION NUMBER:		0001231919-07-000111
CONFORMED SUBMISSION TYPE:	4/A
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070803
FILED AS OF DATE:		20071113
DATE AS OF CHANGE:		20071113

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PHARMATHENE, INC
		CENTRAL INDEX KEY:			0001326190
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				202726770
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE PARK PLACE, SUITE 450
		CITY:			ANNAPOLIS
		STATE:			MD
		ZIP:			21401
		BUSINESS PHONE:		410 269 2600

	MAIL ADDRESS:	
		STREET 1:		ONE PARK PLACE, SUITE 450
		CITY:			ANNAPOLIS
		STATE:			MD
		ZIP:			21401

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HEALTHCARE ACQUISITION CORP
		DATE OF NAME CHANGE:	20050505

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Mirabelli Christopher
		CENTRAL INDEX KEY:			0001262326

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237238

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		609-430-3900

	MAIL ADDRESS:	
		STREET 1:		55 CAMBRIDGE PARKWAY
		STREET 2:		SUITE 301
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER NAME:	
		FORMER CONFORMED NAME:	MIRAELLI CHRISTOPHER
		DATE OF NAME CHANGE:	20030904

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LAWLOR AUGUSTINE
		CENTRAL INDEX KEY:			0001262327

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237239

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		609-430-3900

	MAIL ADDRESS:	
		STREET 1:		55 CAMBRIDGE PARKWAY
		STREET 2:		SUITE 301
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			WERNER HAROLD R
		CENTRAL INDEX KEY:			0001013603

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237240

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		609-430-3900

	MAIL ADDRESS:	
		STREET 1:		C/O HEALTHCARE VENTURES LLC
		STREET 2:		44 NASSAU STREET
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08542

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CAVANAUGH JAMES H
		CENTRAL INDEX KEY:			0001013473
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0731

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237242

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		6094303930

	MAIL ADDRESS:	
		STREET 1:		44 NASSAU ST
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08542

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HealthCare Partners VII, L.P.
		CENTRAL INDEX KEY:			0001330957
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237243

	BUSINESS ADDRESS:	
		STREET 1:		44 NASSAU STREET
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08542
		BUSINESS PHONE:		609-430-3913

	MAIL ADDRESS:	
		STREET 1:		44 NASSAU STREET
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			08542

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HEALTHCARE VENTURES VII LP
		CENTRAL INDEX KEY:			0001202615

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237244

	BUSINESS ADDRESS:	
		STREET 1:		44 NASSAU STREET
		CITY:			PRINCETON
		STATE:			NJ
		ZIP:			085424511
		BUSINESS PHONE:		6094303900

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LITTLECHILD JOHN W
		CENTRAL INDEX KEY:			0001013469

	FILING VALUES:
		FORM TYPE:		4/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		071237241

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		609-430-3900

	MAIL ADDRESS:	
		STREET 1:		55 CAMBRIDGE PARKWAY
		STREET 2:		SUITE 301
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
</SEC-HEADER>
<DOCUMENT>
<TYPE>4/A
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4/A</documentType>

    <periodOfReport>2007-08-03</periodOfReport>

    <dateOfOriginalSubmission>2007-08-07</dateOfOriginalSubmission>

    <issuer>
        <issuerCik>0001326190</issuerCik>
        <issuerName>PHARMATHENE, INC</issuerName>
        <issuerTradingSymbol>HAQ</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001202615</rptOwnerCik>
            <rptOwnerName>HEALTHCARE VENTURES VII LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O HEALTHCARE VENTURES LLC</rptOwnerStreet1>
            <rptOwnerStreet2>44 NASSAU STREET</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08542</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001330957</rptOwnerCik>
            <rptOwnerName>HealthCare Partners VII, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O HEALTHCARE VENTURES LLC</rptOwnerStreet1>
            <rptOwnerStreet2>44 NASSAU STREET</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08542</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001013473</rptOwnerCik>
            <rptOwnerName>CAVANAUGH JAMES H</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O HEALTHCARE VENTURES LLC</rptOwnerStreet1>
            <rptOwnerStreet2>44 NASSAU STREET</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08542</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001013469</rptOwnerCik>
            <rptOwnerName>LITTLECHILD JOHN W</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>55 CAMBRIDGE PARKWAY</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 301</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001013603</rptOwnerCik>
            <rptOwnerName>WERNER HAROLD R</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O HEALTHCARE VENTURES LLC</rptOwnerStreet1>
            <rptOwnerStreet2>44 NASSAU STREET</rptOwnerStreet2>
            <rptOwnerCity>PRINCETON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>08542</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001262327</rptOwnerCik>
            <rptOwnerName>LAWLOR AUGUSTINE</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>55 CAMBRIDGE PARKWAY</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 301</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001262326</rptOwnerCik>
            <rptOwnerName>Mirabelli Christopher</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>55 CAMBRIDGE PARKWAY</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 301</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $.0001 par value per share</value>
            </securityTitle>
            <transactionDate>
                <value>2007-08-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>125000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>7.66</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>250000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $.0001 par value per share</value>
            </securityTitle>
            <transactionDate>
                <value>2007-08-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F2"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3067243</value>
                    <footnoteId id="F2"/>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3317243</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>8% Convertible Note</value>
                <footnoteId id="F3"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>10.00</value>
                <footnoteId id="F3"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-08-03</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F3"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionTotalValue>
                    <value>1815056.92</value>
                </transactionTotalValue>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F3"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <value>2009-08-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>181505</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <valueOwnedFollowingTransaction>
                    <value>1815056.92</value>
                </valueOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F1"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">These securities are owned by HealthCare Ventures VII, L.P. (&quot;HCVVII&quot;). These securities are indirectly beneficially owned by HealthCare Partners VII, L.P. (&quot;HCPVII&quot;), the General Partner of HCVVII, and each of James Cavanaugh, Harold Werner, John Littlechild, Christopher Mirabelli and Augustine Lawlor, the general partners of HCPVII. Drs. Cavanaugh and Mirabelli and Messrs. Werner, Littlechild and Lawlor disclaim beneficial ownership of those securities in which they do not have a pecuniary interest and this report shall not be deemed an admission that they are the beneficial owners of these securities for purposes of Section 16. In addition, James Cavanaugh became a Director of the Issuer on August 6, 2007. Does not include options to purchase (i) 2,759 shares of the Issuer's  Common Stock held by James Cavanaugh; and (ii) 1,655 shares of the Issuer's Common Stock held by Harold Werner. Eric Aguiar is no longer a general  partner of HCPVII as of the date of thi
s filing.</footnote>
        <footnote id="F2">These securities were received in exchange for an aggregate of 23,353,729 shares of Series A, Series B and Series C Convertible Preferred Stock of PharmAthene, Inc. in connection with the merger of PAI Acquisition Corp., a wholly-owned subsidiary of HealthCare Acquisition Corp. (now known as PharmAthene, Inc.) into PharmAthene, Inc. (the &quot;Merger&quot;). This amendment is being filed to correct the total number of shares of the Issuer's Common Stock issued to the Reporting Persons in the Merger.</footnote>
        <footnote id="F3">This Note was received in the Merger in exchange for a note of PharmAthene, Inc. in the principal amount of $1,705,724.61 (plus accrued interest).  This amendment is being filed to correct the principal amount of the Note (and the underlying shares) received by the Reporting Persons in the Merger.</footnote>
        <footnote id="F4">Immediately convertible into shares of Common Stock of the Issuer at the rate of $10.00 per share.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Administrative Partner, HealthCare Ventures VII, L.P.</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Administrative Partner for HealthCare Partners VII, L.P.</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Attorney-in-Fact for James H. Cavanaugh</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Attorney-in-Fact for John Littlechild</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Attorney-in-Fact for Harold Werner</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Attorney-in-Fact for Augustine Lawlor</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>S/Jeffrey Steinberg, Attorney-in-Fact for Christopher Mirabelli</signatureName>
        <signatureDate>2007-11-07</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----