Goodwill and Intangible Assets - Schedule of Intangible Assets (Detail) - USD ($)	9 Months Ended	12 Months Ended
	Sep. 30, 2017	Dec. 31, 2016
Schedule Of Intangible Assets [Line Items]
Total intangible assets, Gross Carrying Value	$ 39,058,564	$ 15,386,473
Intangible assets subject to amortization, Gross Carrying Value	957,088	909,454
Intangible assets subject to amortization, Accumulated Amortization	(472,165)	(431,756)
Intangible assets subject to amortization, Net Book Value	484,923	477,698
Total intangible assets, Net Book Value	38,586,399	14,954,717
IPR&D [Member]
Schedule Of Intangible Assets [Line Items]
Intangible assets, Net Book Value	38,101,476	14,477,019
Internally Developed Patents [Member]
Schedule Of Intangible Assets [Line Items]
Intangible assets subject to amortization, Gross Carrying Value	672,088	624,454
Intangible assets subject to amortization, Accumulated Amortization	(239,211)	(211,956)
Intangible assets subject to amortization, Net Book Value	$ 432,877	$ 412,498
Internally Developed Patents [Member] | Minimum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	6 years	6 years
Internally Developed Patents [Member] | Maximum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	10 years	10 years
Acquired Licenses [Member]
Schedule Of Intangible Assets [Line Items]
Intangible assets subject to amortization, Gross Carrying Value	$ 285,000	$ 285,000
Intangible assets subject to amortization, Accumulated Amortization	(232,954)	(219,800)
Intangible assets subject to amortization, Net Book Value	$ 52,046	$ 65,200
Acquired Licenses [Member] | Minimum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	16 years	16 years
Acquired Licenses [Member] | Maximum [Member]
Schedule Of Intangible Assets [Line Items]
Estimated Useful Lives	20 years	20 years