Income Taxes (Details 1) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income Taxes [Line Items]
Statutory federal tax provision (benefit)	$ 71,758,245	$ (1,148,846)	$ (3,363,841)
State income tax (benefit), net of federal benefit	10,323,810	(124,626)	(450,656)
Other permanent differences	6,211	6,909	(6,274)
Foreign rate differential	4,150	68,482	7,913
Write-off of expired/forfeited options and conversion of notes	181,958	1,049,765	380,689
Rate change	(1,429,996)	1,218	794,807
Lobbying costs	198,491	1,047	57,517
Write-off of tax basis in UK subsidiary	(6,288,553)	0	0
Research and development tax credit	(817,832)	0	0
Other prior year adjustments	0	2,949	(308)
Subtotal	73,936,484	(143,102)	(2,580,153)
Decrease (increase) in valuation allowance	(62,767,108)	204,848	2,641,899
Income tax provision	$ 11,169,376	$ 61,746	$ 61,746
Federal statutory rate	35.00%	34.00%	34.00%