CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Contract revenue	$ 5,230,196	$ 10,640,660	$ 10,190,205
Operating expenses:
Research and development	4,836,035	5,133,512	9,319,828
General and administrative	11,515,071	6,222,185	10,911,724
Restructuring expense	0	2,546,159	0
Depreciation	143,437	141,604	149,958
Total operating expenses	16,494,543	14,043,460	20,381,510
Loss from operations	(11,264,347)	(3,402,800)	(10,191,305)
Other income (expense):
Interest income (expense), net	168,150	(54,581)	(210,399)
Realization of cumulative translation adjustment	0	(229,192)	0
Change in fair value of derivative instruments	(957,070)	299,477	508,817
Other income - litigation	217,068,969	0	0
Other income (expense)	7,847	8,137	(762)
Total other income (expense)	216,287,896	23,841	297,656
Income (loss) before income taxes	205,023,549	(3,378,959)	(9,893,649)
Income tax provision	(11,169,376)	(61,746)	(61,746)
Net income (loss)	$ 193,854,173	$ (3,440,705)	$ (9,955,395)
Basic net income (loss) per share	$ 2.97	$ (0.05)	$ (0.17)
Diluted net income (loss) per share	$ 2.95	$ (0.05)	$ (0.17)
Weighted-average shares used in calculation of basic net income (loss) per share	65,306,962	63,986,013	57,535,325
Weighted-average shares used in calculation of diluted net income (loss) per share	65,657,802	63,986,013	57,535,325