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Summary of Significant Accounting Policies (Details 1) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Allocated Share-based Compensation Expense $ 166,795 $ 133,604 $ 348,720 $ 333,231
Research and development [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Allocated Share-based Compensation Expense 23,181 12,490 52,474 73,225
General and administrative [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Allocated Share-based Compensation Expense $ 143,614 $ 121,114 296,246 313,747
Restructuring benefit [Member]        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Allocated Share-based Compensation Expense     $ 0 $ (53,741)