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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS [Abstract]        
Contract revenue $ 1,155,839 $ 962,451 $ 9,374,155 $ 8,363,909
Operating expenses:        
Research and development 1,125,865 1,728,929 3,962,019 7,528,616
General and administrative 1,231,035 $ 3,192,427 5,246,396 $ 8,289,788
Restructuring expense 422,482 2,519,273
Depreciation 35,005 $ 37,125 108,798 $ 113,272
Total operating expenses 2,814,387 4,958,481 11,836,486 15,931,676
Loss from operations (1,658,548) (3,996,030) (2,462,331) (7,567,767)
Other income (expense):        
Interest expense, net $ (9,888) $ (46,930) (48,492) $ (173,356)
Realization of cumulative translation adjustment (229,192)
Change in fair value of derivative instruments $ 359,796 $ (560,487) 577,426 $ 464,703
Other income (expense) (691) 80 6,594 (1,470)
Total other income (expense) 349,217 (607,337) 306,336 289,877
Net loss before income taxes (1,309,331) (4,603,367) (2,155,995) (7,277,890)
Income tax provision (15,437) (25,068) (46,310) (48,105)
Net loss $ (1,324,768) $ (4,628,435) $ (2,202,305) $ (7,325,995)
Basic and diluted net loss per share $ (0.02) $ (0.08) $ (0.03) $ (0.13)
Weighted average shares used in calculation of basic and diluted net loss per share 64,187,618 58,952,731 63,858,500 55,577,550