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Summary of Significant Accounting Policies (Schedule of Share-based Compensation Expense) (Details) (USD $)
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Total share-based compensation expense $ 1,362,716 $ 1,894,099 $ 2,565,961
Unrecognized share-based compensation expense related to unvested awards 1,300,000    
Unrecognized share-based compensation expense related to unvested awards expected to be recognized in the period 1 year 9 months    
Proceeds from stock options exercised 74,796 38,984 118,309
Research and Development [Member]
     
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Total share-based compensation expense 333,735 518,375 754,554
General and Administrative Expense [Member]
     
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]      
Total share-based compensation expense $ 1,028,981 $ 1,375,724 $ 1,811,407