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CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Contract revenue $ 4,295,400 $ 6,316,998 $ 10,770,538 $ 12,466,050 $ 25,175,887 $ 24,266,274 $ 20,993,605
Operating expenses:              
Research and development 3,402,545 4,918,655 8,636,020 9,624,012 19,509,629 21,219,853 20,875,536
General and administrative 2,332,730 2,780,099 4,612,525 5,728,580 11,628,732 14,311,079 18,015,761
Depreciation and amortization (including $4,635,489 impairment charges in 2010) 41,854 76,448 94,456 162,358 303,916 461,073 5,655,865
Total operating expenses 5,777,129 7,775,202 13,343,001 15,514,950 31,442,277 35,992,005 44,547,162
Loss from operations (1,481,729) (1,458,204) (2,572,463) (3,048,900) (6,266,390) (11,725,731) (23,553,557)
Other income (expenses):              
Interest income 1,656 4,819 2,439 7,807 17,808 16,660 6,955
Interest expense (100,027) (111,353) (199,818) (114,381) (342,561) (54,573) (5,936,480)
Gain on sale of assets held for sale                781,760   
Realization of cumulative translation adjustment             1,227,656      
Change in fair value of derivative instruments 352,824 823,809 (552,953) (167,853) 591,039 7,144,983 (5,457,550)
Other income (expense) 2,110 519 (4,013) 53,434 47,862 39,328 91,355
Total other income (expense) 256,563 717,794 (754,345) (220,993) 1,541,804 7,928,158 (11,295,720)
Net loss before provision for income taxes (1,225,166) (740,410) (3,326,808) (3,269,893) (4,724,586) (3,797,573) (34,849,277)
Provision for income taxes (11,206) (16,133) (20,949) (166,538) (195,529)      
Net loss $ (1,236,372) $ (756,543) $ (3,347,757) $ (3,436,431) $ (4,920,115) $ (3,797,573) $ (34,849,277)
Basic and diluted net loss per share $ (0.02) $ (0.02) $ (0.07) $ (0.07) $ (0.10) $ (0.08) $ (1.08)
Weighted average shares used in calculation of basic and diluted net loss per share 49,749,167 48,325,945 49,058,014 48,297,919 48,323,067 47,331,763 32,309,621