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Summary of Significant Accounting Policies (Tables)
6 Months Ended 12 Months Ended
Jun. 30, 2013
Dec. 31, 2012
Summary of Significant Accounting Policies [Abstract]    
Estimated Useful Life of Property and Equipment  

Property and equipment are depreciated using the straight-line method over the estimated useful lives of the respective assets as follows:

     
Asset Category   Estimated Useful Life
(in Years)
Leasehold improvements   8 - 10
Furniture and office equipment   5
Computer and other equipment   3 - 5
Schedule of Share-based Compensation Expense

Share-based compensation expense for the three months ended June 30, 2013 and 2012 was:

         
    Three months ended June 30,
     2013   2012
Research and development   $ 73,859     $ 127,076  
General and administrative     250,149       384,965  
Total share-based compensation expense   $ 324,008     $ 512,041  

Share-based compensation expense for the six months ended June 30, 2013 and 2012 was:

         
    Six months ended June 30,
     2013   2012
Research and development   $ 162,493     $ 244,143  
General and administrative     490,096       816,562  
Total share-based compensation expense   $ 652,589     $ 1,060,705

Share-based compensation expense for 2012, 2011 and 2010 is as follows:

             
    Year ended December 31,
     2012   2011   2010
Research and development   $ 518,375     $ 754,554     $ 1,008,368  
General and administrative     1,375,724       1,811,407       1,504,791  
Total share-based compensation expense   $ 1,894,099     $ 2,565,961     $ 2,513,159