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Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2012
Summary of Significant Accounting Policies [Abstract]  
Estimated Useful Life of Property and Equipment

 

      Estimated Useful Life  
Asset Category     (in Years)  
       
Leasehold improvements     8- 10  
Furniture and office equipment     5  
Computer and other equipment     3- 5  
Schedule of Share-based Compensation Expense

 

    Year ended December 31,  
    2012     2011     2010  
                   
Research and development   $ 518,375     $ 754,554     $ 1,008,368  
General and administrative     1,375,724       1,811,407       1,504,791  
Total share-based compensation expense   $ 1,894,099     $ 2,565,961     $ 2,513,159