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Condensed Consolidated Statements of Operations (USD $)
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Revenue $ 6,696,126 $ 5,260,057 $ 19,162,176 $ 18,026,619
Operating expenses:        
Research and development 5,138,622 4,884,231 14,762,634 16,688,703
General and administrative 3,275,428 3,283,246 9,004,008 11,632,272
Depreciation and amortization 72,453 114,494 234,811 348,813
Total operating expenses 8,486,503 8,281,971 24,001,453 28,669,788
Loss from operations (1,790,377) (3,021,914) (4,839,277) (10,643,169)
Other income (expense):        
Interest income 5,727 3,961 13,534 10,496
Interest expense (112,529) (9,932) (226,910) (40,540)
Realization of cumulative translation adjustment 1,227,656   1,227,656  
Change in fair value of derivative instruments 508,971 2,898,869 341,118 6,075,555
Other income (expense) (31,312) 95,520 22,122 50,892
Total other income (expense) 1,598,513 2,988,418 1,377,520 6,096,403
Net loss before provision for income taxes (191,864) (33,496) (3,461,757) (4,546,766)
Provision for income taxes (22,072)   (188,610)  
Net loss $ (213,936) $ (33,496) $ (3,650,367) $ (4,546,766)
Basic and diluted net loss per share $ 0.00 $ 0.00 $ (0.08) $ (0.10)
Weighted average shares used in calculation of basic and diluted net loss per share 48,345,984 48,194,035 48,314,058 47,041,027