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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 CpSMxdTFb8fC1JNJ8kqlNvYQ6qrG3TUwGxSwH7cR+0Le2dyDLylfzVGriQrBcT9V
 9X7yxakai7CDwTTRPbCJYQ==

<SEC-DOCUMENT>0001144204-10-029117.txt : 20100519
<SEC-HEADER>0001144204-10-029117.hdr.sgml : 20100519
<ACCEPTANCE-DATETIME>20100519202940
ACCESSION NUMBER:		0001144204-10-029117
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100517
FILED AS OF DATE:		20100519
DATE AS OF CHANGE:		20100519

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PHARMATHENE, INC
		CENTRAL INDEX KEY:			0001326190
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				202726770
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		ONE PARK PLACE, SUITE 450
		CITY:			ANNAPOLIS
		STATE:			MD
		ZIP:			21401
		BUSINESS PHONE:		410 269 2600

	MAIL ADDRESS:	
		STREET 1:		ONE PARK PLACE, SUITE 450
		CITY:			ANNAPOLIS
		STATE:			MD
		ZIP:			21401

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HEALTHCARE ACQUISITION CORP
		DATE OF NAME CHANGE:	20050505

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SCHAFFER DERACE L
		CENTRAL INDEX KEY:			0001031735
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MISC HEALTH & ALLIED SERVICES, NEC [8090]
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-32587
		FILM NUMBER:		10846514

	MAIL ADDRESS:	
		STREET 1:		C/O ALLION HEALTHCARE, INC.
		STREET 2:		1660 WALT WHITMAN ROAD, SUITE 105
		CITY:			MELVILLE
		STATE:			NY
		ZIP:			11747
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>v185967_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-05-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001326190</issuerCik>
        <issuerName>PHARMATHENE, INC</issuerName>
        <issuerTradingSymbol>PIP</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001031735</rptOwnerCik>
            <rptOwnerName>SCHAFFER DERACE L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O PHARMATHENE, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>ONE PARK PLACE, SUITE 450</rptOwnerStreet2>
            <rptOwnerCity>ANNAPOLIS</rptOwnerCity>
            <rptOwnerState>MD</rptOwnerState>
            <rptOwnerZipCode>21401</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $0.0001 par value per share</value>
            </securityTitle>
            <transactionDate>
                <value>2010-05-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>16747</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.4206</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>757911</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, $0.0001 par value per share</value>
            </securityTitle>
            <transactionDate>
                <value>2010-05-18</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>83253</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.4981</value>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>841164</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices
 ranging from $1.34 to $1.45, inclusive. The reporting person undertakes to provide to PharmAthene, Inc., any security holder
 of PharmAthene, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the
 number of shares sold at each separate price within the ranges set forth in footnotes (1) and (2) to this Form 4.</footnote>
        <footnote id="F2">The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices
 ranging from $1.45 to $1.50, inclusive.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Roland S. Chase, attorney in fact</signatureName>
        <signatureDate>2010-05-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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