-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Jfn5UDDaIiAgnuPqCJ47NmVdEJwP/v+r28Wi9jWyfXxgrc5eatndBA+zESoaE+Ki
 0NmWn5BJK9TClL7tdew6EA==

<SEC-DOCUMENT>0001104659-09-049246.txt : 20090812
<SEC-HEADER>0001104659-09-049246.hdr.sgml : 20090812
<ACCEPTANCE-DATETIME>20090812154519
ACCESSION NUMBER:		0001104659-09-049246
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20090812
DATE AS OF CHANGE:		20090812
EFFECTIVENESS DATE:		20090812

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PHARMATHENE, INC
		CENTRAL INDEX KEY:			0001326190
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				202726770
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-124075
		FILM NUMBER:		091006766

	BUSINESS ADDRESS:	
		STREET 1:		ONE PARK PLACE, SUITE 450
		CITY:			ANNAPOLIS
		STATE:			MD
		ZIP:			21401
		BUSINESS PHONE:		410 269 2600

	MAIL ADDRESS:	
		STREET 1:		ONE PARK PLACE, SUITE 450
		CITY:			ANNAPOLIS
		STATE:			MD
		ZIP:			21401

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	HEALTHCARE ACQUISITION CORP
		DATE OF NAME CHANGE:	20050505
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0502</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001326190</cik>
        <entityName>PHARMATHENE, INC</entityName>
        <issuerAddress>
            <street1>One Park Place</street1>
            <street2>Suite 450</street2>
            <city>Annapolis</city>
            <stateOrCountry>MD</stateOrCountry>
            <zipCode>21401</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>(410) 269-2600</issuerPhoneNumber>
        <issuerPreviousNameList>
            <previousName>Healthcare Acquisition Corp.</previousName>
        </issuerPreviousNameList>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <withinFiveYears>true</withinFiveYears>
            <value>2005</value>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <middleName>P.</middleName>
                <lastName>Wright</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName></middleName>
                <lastName>Gill</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>James</firstName>
                <middleName>H.</middleName>
                <lastName>Cavanaugh</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Steven</firstName>
                <middleName></middleName>
                <lastName>St. Peter</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>John</firstName>
                <middleName></middleName>
                <lastName>Pappajohn</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joel</firstName>
                <middleName></middleName>
                <lastName>McCleary</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Derace</firstName>
                <middleName>L.</middleName>
                <lastName>Schaffer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Christopher</firstName>
                <middleName>C.</middleName>
                <lastName>Camut</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Francesca</firstName>
                <middleName></middleName>
                <lastName>Cook</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joan</firstName>
                <middleName></middleName>
                <lastName>Fusco</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Jordan</firstName>
                <middleName>P.</middleName>
                <lastName>Karp</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Valerie</firstName>
                <middleName>C.</middleName>
                <lastName>Riddle</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Wayne</firstName>
                <middleName></middleName>
                <lastName>Morges</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Eric</firstName>
                <middleName>I.</middleName>
                <lastName>Richman</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o PharmAthene, Inc.</street1>
                <street2>One Park Place, Suite 450</street2>
                <city>Annapolis</city>
                <stateOrCountry>MD</stateOrCountry>
                <zipCode>24101</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>$25,000,001 - $100,000,000</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2009-07-28</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>6000</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>19295802</totalOfferingAmount>
            <totalAmountSold>19295802</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>22</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>PharmAthene, Inc.</issuerName>
                <signatureName>/s/ Jordan P. Karp</signatureName>
                <nameOfSigner>Jordan P. Karp</nameOfSigner>
                <signatureTitle>Senior Vice President and General Counsel</signatureTitle>
                <signatureDate>2009-08-11</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----