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Description of Business
6 Months Ended
Jun. 30, 2021
Organization Consolidation And Presentation Of Financial Statements [Abstract]  
Description of Business

1.     Description of Business

Organization

We were incorporated in Illinois on October 7, 2002 under the name ZelleRx Corporation. On January 22, 2010, we changed our name to Conkwest, Inc. In March 2014, we formed Conkwest, Inc., our wholly-owned subsidiary in the state of Delaware, or Conkwest Delaware, for the purposes of changing the state of our incorporation to the state of Delaware. In March 2014, we merged with and into Conkwest Delaware, with Conkwest Delaware surviving the merger. On July 10, 2015, we changed our name to NantKwest, Inc. On March 9, 2021, we completed a merger with NantCell, Inc. (formerly known as ImmunityBio, Inc., a private company) (“NantCell”), and we changed our name to ImmunityBio, Inc. Our principal executive offices are located in San Diego, California. In these notes to the unaudited condensed consolidated financial statements, the terms “ImmunityBio,” “the company,” “the combined company,” “we,” “us,” and “our” refer to ImmunityBio and subsidiaries.

We established ImmunityBio to advance next-generation immunotherapies and address unmet needs within oncology and infectious disease. Our platform is designed to overcome limitations of the current standards of T cell-based immunotherapies, including checkpoint inhibitors and CAR-T cells and is based on our four key modalities: (1) activating natural killer (“NK”), and T cells using antibody cytokine fusion proteins, (2) activating tumoricidal macrophages using low-dose synthetic immunomodulators, (3) generating memory T cells using vaccine candidates developed with our second-generation adenovirus, or hAd5, technology, and (4) off-the-shelf natural killer cells from the NK‑92 cell line and memory-like cytokine-enhanced NK cells (“M‑ceNK”) from allogenic and autologous donors.

We own a broad, clinical-stage immunotherapy pipeline, including an antibody cytokine fusion protein (an IL‑15 superagonist (N‑803) known as Anktiva), an albumin-associated anthracycline synthetic immunomodulator (aldoxorubicin), second-generation adenovirus (“hAd5”) and yeast vaccine technologies (targeting tumor-associated antigens and neoepitopes), off-the-shelf genetically engineered natural killer cell lines inducing cancer and virally infected cell death through a variety of concurrent mechanisms (including innate killing, antibody-mediated killing, and CAR-directed killing), patient specific NK cell product for cancer (M-ceNK), macrophage polarizing peptides, and bi-specific fusion proteins targeting CD20, PD‑L1, TGF‑b and IL‑12. Our immunotherapy clinical pipeline consists of over 40 clinical trials in Phase 1, 2, or 3 development across 19 indications in solid and liquid cancers and infectious diseases. We have an expansive clinical-stage pipeline and intellectual property portfolio with 17 first-in-human assets in 25 Phase II to III clinical trials.

In December 2019, the United States (“U.S.”) Food and Drug Administration (“FDA”) granted Breakthrough Therapy designation to Anktiva for bacillus Calmette-Guérin (“BCG”) unresponsive carcinoma in situ non-muscle invasive bladder cancer. Based on patient readout data that was submitted with our application to obtain our Breakthrough Therapy designation, Anktiva achieved its primary endpoint of complete response rate at any time in the ongoing registrational Phase II / III trial. Other indications currently with registration-potential studies include BCG unresponsive papillary bladder cancer, first- and second-line lung cancer, and metastatic pancreatic cancer.

The Merger

On December 21, 2020, we and NantCell entered into an Agreement and Plan of Merger (the “Merger Agreement”), pursuant to which we and NantCell agreed to combine our businesses. The Merger Agreement provided that a wholly-owned subsidiary of the company would merge with and into NantCell (the “Merger”), with NantCell surviving the Merger as a wholly-owned subsidiary of the company.

On March 9, 2021, we completed the Merger pursuant to the terms of the Merger Agreement. Under the terms of the Merger Agreement, at the effective time of the Merger (the “Effective Time”), each share of NantCell common stock, par value $0.001 per share, issued and outstanding immediately prior to the Effective Time, subject to certain exceptions as set forth in the Merger Agreement, was converted automatically into a right to receive 0.8190 (the “Exchange Ratio”) newly issued shares of common stock, par value $0.0001 per share, of the company (“Company Common Stock”), with cash paid in lieu of any fractional shares. At the Effective Time, each share of the company’s common stock issued and outstanding immediately prior to the Effective Time, remained an issued and outstanding share of the combined company. At the Effective Time, each outstanding option, warrant or restricted stock unit to purchase NantCell common stock was converted using the Exchange Ratio into an option, warrant or restricted stock unit, respectively, on the same terms and conditions immediately prior to the Effective Time, to purchase shares of Company Common Stock.

Immediately following the Effective Time, the former stockholders of NantCell held approximately 71.5% of the outstanding shares of Company Common Stock and the stockholders of the company as of immediately prior to the Merger held approximately 28.5% of the outstanding shares of Company Common Stock. As a result of the Merger and immediately following the Effective Time, Dr. Patrick Soon-Shiong, our Executive Chairman, and his affiliates beneficially owned, in the aggregate, approximately 81.8% of the outstanding shares of Company Common Stock. Following the consummation of the Merger, shares of the company’s common stock were listed on the Nasdaq Global Select Market under the symbol “IBRX.”

We incurred costs totaling $23.3 million in connection with the Merger, consisting of financial advisory, legal and other professional fees, of which $13.0 million was recorded during the six months ended June 30, 2021. Merger-related costs are reported in selling, general and administrative expense, on the condensed consolidated statements of operations.

Accounting Treatment of the Merger

The Merger represents a business combination pursuant to Financial Accounting Standards Board (“FASB”) Accounting Standards Codification (“ASC”) Topic 805-50, Mergers, which is accounted for as a transaction between entities under common control as Dr. Soon-Shiong and his affiliates were the controlling stockholders of both the company and NantCell for all of the periods presented in this report. As a result, all of the assets and liabilities of NantCell were combined with ours at their historical carrying amounts on the closing date of the Merger. We have recast our prior period financial statements to reflect the conveyance of NantCell’s common shares as if the Merger had occurred as of the earliest date of the financial statements presented. All material intercompany accounts and transactions have been eliminated in consolidation.

The following tables provide the impact of the change in reporting entity on our unaudited condensed consolidated statements of operations for the three months ended March 31, 2021 and the three and six months ended June 30, 2020, respectively (in thousands):

 

 

 

Three Months Ended

March 31, 2021

 

 

 

(Unaudited)

 

 

 

NantCell

 

 

NantKwest

 

 

Intercompany

Eliminations

 

 

ImmunityBio,

Inc.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Revenue

 

$

183

 

 

$

 

 

$

(44

)

 

$

139

 

Operating expenses:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research and development (including amounts

   with related parties)

 

 

21,509

 

 

 

19,725

 

 

 

(106

)

 

 

41,128

 

Selling, general and administrative (including amounts

   with related parties)

 

 

24,382

 

 

 

20,903

 

 

 

(10

)

 

 

45,275

 

Loss from operations

 

 

(45,708

)

 

 

(40,628

)

 

 

72

 

 

 

(86,264

)

Other (expense) income, net (including amounts

   with related parties)

 

 

(848

)

 

 

6,637

 

 

 

 

 

 

5,789

 

Income tax expense

 

 

 

 

 

(6

)

 

 

 

 

 

(6

)

Net loss

 

$

(46,556

)

 

$

(33,997

)

 

$

72

 

 

$

(80,481

)

 

 

 

Three Months Ended

June 30, 2020

 

 

 

(Unaudited)

 

 

 

NantCell

 

 

NantKwest

 

 

Intercompany

Eliminations

 

 

ImmunityBio,

Inc.

 

Revenue

 

$

1,525

 

 

$

1

 

 

$

(1,090

)

 

$

436

 

Operating expenses:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research and development (including amounts

   with related parties)

 

 

19,384

 

 

 

13,709

 

 

 

(88

)

 

 

33,005

 

Selling, general and administrative (including amounts

   with related parties)

 

 

11,828

 

 

 

6,519

 

 

 

 

 

 

18,347

 

Loss from operations

 

 

(29,687

)

 

 

(20,227

)

 

 

(1,002

)

 

 

(50,916

)

Other (expense) income, net (including amounts

   with related parties)

 

 

(1,195

)

 

 

139

 

 

 

 

 

 

(1,056

)

Income tax expense

 

 

(41

)

 

 

(4

)

 

 

 

 

 

 

(45

)

Net loss

 

$

(30,923

)

 

$

(20,092

)

 

$

(1,002

)

 

$

(52,017

)

 

 

 

Six Months Ended

June 30, 2020

 

 

 

(Unaudited)

 

 

 

NantCell

 

 

NantKwest

 

 

Intercompany

Eliminations

 

 

ImmunityBio,

Inc.

 

Revenue

 

$

1,693

 

 

$

22

 

 

$

(1,114

)

 

$

601

 

Operating expenses:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Research and development (including amounts

   with related parties)

 

 

33,636

 

 

 

26,943

 

 

 

(200

)

 

 

60,379

 

Selling, general and administrative (including amounts

   with related parties)

 

 

15,948

 

 

 

11,892

 

 

 

 

 

 

27,840

 

Loss from operations

 

 

(47,891

)

 

 

(38,813

)

 

 

(914

)

 

 

(87,618

)

Other (expense) income, net (including amounts

   with related parties)

 

 

(2,105

)

 

 

342

 

 

 

 

 

 

(1,763

)

Income tax expense

 

 

(59

)

 

 

(4

)

 

 

 

 

 

(63

)

Net loss

 

$

(50,055

)

 

$

(38,475

)

 

$

(914

)

 

$

(89,444

)