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Collaboration and License Agreements - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
May 31, 2017
Jun. 30, 2015
Feb. 28, 2010
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2004
Licensing Agreement [Line Items]              
Research and development (including amounts with related parties)       $ 64,483,000 $ 49,785,000 $ 55,718,000  
Due to related parties       5,269,000 486,000    
Milestone payments       0      
Rush University Medical Center License Agreement              
Licensing Agreement [Line Items]              
Period of license agreement             12 years
Minimum annual royalty payment             $ 25,000
Payments in license agreement             2,500,000
Minimum sales milestone of license for first year             $ 300,000
Viracta Therapeutics, Inc.              
Licensing Agreement [Line Items]              
License agreement termination notice period 90 days            
Viracta Therapeutics, Inc. | Minimum              
Licensing Agreement [Line Items]              
Milestone Payment Amount $ 10,000,000.0            
Viracta Therapeutics, Inc. | Maximum              
Licensing Agreement [Line Items]              
Milestone Payment Amount $ 25,000,000.0            
ImmunityBio              
Licensing Agreement [Line Items]              
Research and development (including amounts with related parties)       $ 300,000 100,000 100,000  
Related party, agreement renewal term   1 year          
Joint COVID 19 Collaboration Development Agreement              
Licensing Agreement [Line Items]              
Term of agreement       5 years      
Additional term of agreement renewable upon mutual agreement       5 years      
Joint COVID 19 Collaboration Development Agreement | Sales              
Licensing Agreement [Line Items]              
Profit sharing percentage       60.00%      
Joint COVID 19 Collaboration Development Agreement | ImmunityBio              
Licensing Agreement [Line Items]              
Research and development (including amounts with related parties)       $ 8,400,000      
Due to related parties       3,300,000      
Joint COVID 19 Collaboration Development Agreement | ImmunityBio | Program Equipment Related Costs              
Licensing Agreement [Line Items]              
Research and development (including amounts with related parties)       5,000,000.0      
Joint COVID 19 Collaboration Development Agreement | ImmunityBio | Net Program Related Costs              
Licensing Agreement [Line Items]              
Research and development (including amounts with related parties)       $ 3,400,000      
Joint COVID 19 Collaboration Development Agreement | ImmunityBio | Sales              
Licensing Agreement [Line Items]              
Profit sharing percentage       40.00%      
Clinical Trial Cost Allocation Agreement | ImmunityBio              
Licensing Agreement [Line Items]              
Research and development (including amounts with related parties)       $ 1,100,000 35,700    
Due to related parties       300,000 0    
Related party, agreement renewal term   1 year          
Precigen License Agreement              
Licensing Agreement [Line Items]              
Milestone Payment Amount       0 0 0  
License agreement term (years)     17 years        
Agreement one time fee     $ 400,000        
Milestone payments       $ 0 $ 0 $ 0  
Precigen License Agreement | First IND Filing              
Licensing Agreement [Line Items]              
Milestone Payment Amount     100,000        
Precigen License Agreement | First Phase II Clinical Trial              
Licensing Agreement [Line Items]              
Milestone Payment Amount     100,000        
Precigen License Agreement | First Phase III Clinical Trial              
Licensing Agreement [Line Items]              
Milestone Payment Amount     400,000        
Precigen License Agreement | Commercial Sale Related to Licensed Products              
Licensing Agreement [Line Items]              
Milestone Payment Amount     $ 500,000