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Spin-out of Brink Biologics and Coneksis - Additional Information (Detail) - Spinout - USD ($)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Brink Biologics Inc    
Related Party Transaction [Line Items]    
Royalty revenue $ 21,000 $ 11,000
Number of days due for payment 30 days  
Invoiced for services $ 100,000 22,000
Amount owed to the company $ 100,000  
Coneksis    
Related Party Transaction [Line Items]    
Number of days due for payment 30 days  
Invoiced for services $ 19,000 $ 6,000
Amount owed to the company $ 25,000