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STATEMENTS OF CASH FLOWS - USD ($)
9 Months Ended 12 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
CASH FLOWS FROM OPERATING ACTIVITIES          
Net loss $ (4,509,172) $ (4,160,693) $ (5,749,382) $ (4,407,208) $ (4,845,432)
Adjustments to reconcile net loss to net cash used in operating activities          
Warrants issued for services 62,731 175,621 416,934 174,359 91,263
Stock options issued for services 339,076 694,621 794,738 436,228 1,339,692
Common stock issued for services and fees 135,333 136,557 270,343 295,885 48,963
Depreciation and amortization and noncash patent expenses 322,495 214,573 325,946 195,610 179,907
(Gain) loss on disposal of property and equipment 10,084 (644)
(Increase) decrease in assets          
Prepaid expenses and other current assets 268,560 (38,839) (447,977) 127,549 (136,264)
(Decrease) increase in liabilities          
Accounts payable (31,610) 19,591 (58,395) 32,175 (145,313)
Accounts payable and accrued expenses- related parties 43,962 12,303 3,211 490 (5,254)
Accrued expenses (46,305) 72,668 34,886 (7,736) 31,683
Net cash used in operating activities (3,404,846) (2,873,598) (4,409,696) (3,153,292) (3,440,755)
CASH FLOWS FROM INVESTING ACTIVITIES          
Cost of intangibles (371,320) (38,662) (81,743) (64,096) (29,577)
Purchase of property and equipment (897,774) (88,649) (183,789) (129,163) (279,903)
Sale of property and equipment 2,500 19,500
Net cash used in investing activities (1,266,594) (127,311) (265,532) (173,759) (309,480)
CASH FLOWS FROM FINANCING ACTIVITIES          
Exercise of options and warrants 161,500 502,500 502,500
Issuance of common stock, institutional investor 3,612,400 3,439,060 5,722,060 1,553,190
Issuance of common stock, private placement     4,315,000
Repayment of equipment purchase payable (380,470) (17,839) (23,849)
Net cash provided by financing activities 3,393,430 3,923,721 6,200,711 1,553,190 4,315,000
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS (1,278,010) 922,812 1,525,483 (1,773,861) 564,765
CASH AND CASH EQUIVALENTS - BEGINNING OF PERIOD 3,482,327 1,956,844 1,956,844 3,730,705 3,165,940
CASH AND CASH EQUIVALENTS - END OF PERIOD 2,204,317 2,879,656 3,482,327 1,956,844 3,730,705
Supplemental Disclosure of Non-cash investing and financing activities:          
Equipment acquisition funded by liability 107,033 749,316
Common stock for service, paid in advance $ 36,250 $ 36,250