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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Operating activities    
Net loss $ (21,784) $ (46,087)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 51 51
Stock-based compensation 4,159 3,774
Non-cash interest expense 718 729
Non-cash change in fair value of PIPE Warrant liability 0 (199)
Amortization of premium and discount on investments 51 50
Changes in operating assets and liabilities:    
Trade receivables, net (8,906) (8,303)
Partnership receivables 743 (8)
Inventory 550 (1,252)
Prepaid expenses and other current assets 1,690 (651)
Operating lease right-of-use asset 97 343
Other non-current assets (45) (100)
Accounts payable 2,327 1,544
Accrued clinical trial costs and contract manufacturing 5,543 1,984
Accrued compensation and benefits 765 1,075
Other accrued liabilities 4,151 3,946
Operating lease liability (9) (8)
Deferred revenue (578) (1,480)
Deferred research and development reimbursements 0 (164)
Operating lease liability, non-current 0 (317)
Net cash used in operating activities (10,477) (45,073)
Investing activities    
Purchases of marketable securities (8,979) (28,128)
Proceeds from maturities and sales of marketable securities 25,715 2,900
Net cash provided by (used in) investing activities 16,736 (25,228)
Financing activities    
Proceeds from issuance of common stock, net of issuance costs 0 55,095
Proceeds from warrant exercises 0 3,092
Proceeds from issuance of stock for stock-based compensation arrangements 597 68
Proceeds from issuance of loan payable 0 20,000
Payment of loan maturity fees (Note 6) 0 (790)
Payment of debt issuance costs 0 (85)
Net cash provided by financing activities 597 77,380
Net increase in cash and cash equivalents 6,856 7,079
Cash and cash equivalents at beginning of period 70,542 61,761
Cash and cash equivalents at end of period 77,398 68,840
Supplemental cash flow information    
Cash paid for interest $ 3,116 $ 2,035