Quarterly Results (Unaudited)

12 Months Ended

Dec. 31, 2016

Quarterly Financial Information Disclosure [Abstract]

Quarterly Results (Unaudited)

(14) Quarterly Results (Unaudited)

	Three Month Ended
	March 31, 2016			June 30, 2016			September 30, 2016			December 31, 2016
	(in thousands, expect per share data)
	(unaudited)
Collaboration and licensing revenue	$	1,203		$	193		$	992		$	127
Operating expenses		8,435			7,335			6,585			9,553
Loss from operations		(7,232	)		(7,142	)		(5,593	)		(9,426	)
Change in fair value warranty liability		—			(996	)		1,178			4,569
Other expense, net		(378	)		(468	)		(551	)		(748	)
Net loss	$	(7,710	)	$	(8,606	)	$	(4,966	)	$	(5,605	)
Net loss per share	$	(0.13	)	$	(0.13	)	$	(0.07	)	$	(0.07	)
	Three Month Ended
	March 31, 2015			June 30, 2015			September 30, 2015			December 31, 2015
	(in thousands, expect per share data)
	(unaudited)
Collaboration and licensing revenue	$	134		$	134		$	15,158		$	3,598
Restructuring and lease exit		4,333			25			—			—
Operating expenses		5,950			4,730			6,691			9,721
(Loss) income from operations		(10,149	)		(4,621	)		8,467			(6,123	)
Other expense, net		(725	)		(835	)		(553	)		(462	)
Net (loss) income	$	(10,874	)	$	(5,456	)	$	7,914		$	(6,585	)
Net (loss) income per share	$	(0.21	)	$	(0.10	)	$	0.14		$	(0.11	)