Commitments and Contingencies - Additional Information (Detail)		12 Months Ended
	May. 09, 2012 USD ($) ft²	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)	Dec. 31, 2013 USD ($)
Commitment And Contingencies [Line Items]
Rent expense		$ (9,100,000)	$ 4,100,000	$ 9,400,000
Maximum
Commitment And Contingencies [Line Items]
Severance and bonus payment period		18 months
Severance and bonus payment period		18 months
Minimum
Commitment And Contingencies [Line Items]
Severance and bonus payment period		12 months
Severance and bonus payment period		6 months
BMR-650 E KENDALL B LLC
Commitment And Contingencies [Line Items]
Lease agreement, square feet of property leased | ft²	126,065
Lease agreement, initial term	12 years 7 months
Operating lease, maximum lease improvements reimbursement amount	$ 14,900,000
Operating lease, rent expense		$ (9,500,000)	4,300,000	$ 6,700,000
Recognition of deferred rent credits		10,600,000	3,800,000
Lease Cancellable Arrangement
Commitment And Contingencies [Line Items]
Rent expense		$ 200,000
Restructuring and lease exit
Commitment And Contingencies [Line Items]
Rent expense			$ 3,100,000