X0303 4 2010-03-17 0001325879 AVEO PHARMACEUTICALS INC AVEO 0001239241 EVNIN ANTHONY B C/O VENROCK 530 FIFTH AVENUE, 22ND FLOOR NEW YORK NY 10036 1 0 0 0 Common Stock 2010-03-17 4 C 0 725924 A 725924 I By Funds Common Stock 2010-03-17 4 C 0 720521 A 1446445 I By Funds Common Stock 2010-03-17 4 C 0 200514 A 1646959 I By Funds Series A Convertible Preferred Stock 2010-03-17 4 C 0 2903704 0 D Common Stock 725924 0 I No securities owned Series B Convertible Preferred Stock 2010-03-17 4 C 0 2882089 0 D Common Stock 720521 0 I No securities owned Series D Convertible Preferred Stock 2010-03-17 4 C 0 802062 0 D Common Stock 200514 0 I No securities owned Each share of Series A Convertible Preferred Stock, Series B Convertible Preferred Stock and Series D Convertible Preferred Stock automatically converted into shares of common stock on a 0.25 for 1 basis immediately upon the closing of the Issuer's initial public offering. These securities are preferred stock of the Issuer and do not have an expiration date. These securities automatically converted into shares of common stock upon the closing of the Issuer's initial public offering. The shares, on a post conversion basis, are held as follows: 130,666 shares held by Venrock Associates ("VA"), 580,740 shares held by Venrock Associates III, L.P. ("VA3") and 14,518 shares held by Venrock Entrepreneurs Fund III, L.P. ("VEF3"). Dr. Evnin is a general partner of VA. Venrock Management III, LLC ("VM3") is the sole general partner of VA3. VEF Management III, LLC ("VEFM3") is the sole general partner of VEF3. Dr. Evnin is a member of VM3 and VEFM3. Dr. Evnin expressly disclaims beneficial ownership over all shares held by VA, VA3, VEF3, VM3 and VEFM3, except to the extent of his indirect pecuniary interest therein. VM3 and VEFM3 expressly disclaim beneficial ownership over all shares held by VA3 and VEF3, except to the extent of their indirect pecuniary interest therein. The shares, on a post conversion basis, are held as follows: 129,694 shares held by VA, 576,417 shares held by VA3 and 14,410 shares held by VEF3. Dr. Evnin expressly disclaims beneficial ownership over all shares held by VA, VA3, VEF3, VM3 and VEFM3, except to the extent of his indirect pecuniary interest therein. VM3 and VEFM3 expressly disclaim beneficial ownership over all shares held by VA3 and VEF3, except to the extent of their indirect pecuniary interest therein. The shares, on a post conversion basis, are held as follows: 36,092 shares held by VA, 160,412 shares held by VA3 and 4,010 shares held by VEF3. Dr. Evnin expressly disclaims beneficial ownership over all shares held by VA, VA3, VEF3, VM3 and VEFM3, except to the extent of his indirect pecuniary interest therein. VM3 and VEFM3 expressly disclaim beneficial ownership over all shares held by VA3 and VEF3, except to the extent of their indirect pecuniary interest therein. The shares are held as follows: 130,666 shares held by VA, 580,740 shares held by VA3 and 14,518 shares held by VEF3. Dr. Evnin expressly disclaims beneficial ownership over all shares held by VA, VA3, VEF3, VM3 and VEFM3, except to the extent of his indirect pecuniary interest therein. VM3 and VEFM3 expressly disclaim beneficial ownership over all shares held by VA3 and VEF3, except to the extent of their indirect pecuniary interest therein. The shares are held as follows: 260,360 shares held by VA, 1,157,157 shares held by VA3 and 28,928 shares held by VEF3. Dr. Evnin expressly disclaims beneficial ownership over all shares held by VA, VA3, VEF3, VM3 and VEFM3, except to the extent of his indirect pecuniary interest therein. VM3 and VEFM3 expressly disclaim beneficial ownership over all shares held by VA3 and VEF3, except to the extent of their indirect pecuniary interest therein. The shares are held as follows: 296,452 shares held by VA, 1,317,569 shares held by VA3 and 32,938 shares held by VEF3. Dr. Evnin expressly disclaims beneficial ownership over all shares held by VA, VA3, VEF3, VM3 and VEFM3, except to the extent of his indirect pecuniary interest therein. VM3 and VEFM3 expressly disclaim beneficial ownership over all shares held by VA3 and VEF3, except to the extent of their indirect pecuniary interest therein. /s/ Anthony B. Evnin 2010-03-18