Condensed Consolidated Statements of Operations (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Collaboration revenue	$ 26,554	$ 15,622	$ 160,168	$ 26,503
Operating expenses:
Research and development	25,078	25,997	63,095	48,615
General and administrative	6,371	3,835	15,599	6,588
Operating Expenses, Total	31,449	29,832	78,694	55,203
Income (loss) from operations	(4,895)	(14,210)	81,474	(28,700)
Other income and expense:
Other income (expense), net	11	(582)	(45)	130
Interest expense	(946)	(725)	(1,958)	(1,332)
Interest income	99	28	164	35
Other (expense) income, net	(836)	(1,279)	(1,839)	(1,167)
Net income (loss)	$ (5,731)	$ (15,489)	$ 79,635	$ (29,867)
Basic net income (loss) per share
Net income (loss)	$ (0.16)	$ (0.50)	$ 2.19	$ (1.60)
Weighted average number of common shares outstanding	36,849	30,822	36,318	18,649
Diluted net income (loss) per share
Net income (loss)	$ (0.16)	$ (0.50)	$ 2.09	$ (1.60)
Weighted average number of common shares and dilutive common share equivalents outstanding	36,849	30,822	38,120	18,649