X0206 3 2021-03-10 0 0001325879 AVEO PHARMACEUTICALS, INC. AVEO 0001853186 Ferraresso Michael C/O AVEO PHARMACEUTICALS, INC. 30 WINTER STREET BOSTON MA 02108 0 1 0 0 Chief Commercial Officer Common Stock 3284 D Stock Option (right to buy) 28.30 2027-12-04 Common Stock 20000 D Stock Option (right to buy) 30.80 2028-02-01 Common Stock 3740 D Stock Option (right to buy) 6.20 2029-02-06 Common Stock 35064 D Stock Option (right to buy) 5.60 2030-02-05 Common Stock 42499 D Stock Option (right to buy) 9.12 2031-02-05 Common Stock 100000 D 25% of the shares underlying this option vested on December 4, 2018, and the remainder of this option vest in equal monthly installments from December 4, 2018, through December 4, 2021 subject to the Reporting Person's continued service to the Company. The shares underlying this option vest in equal monthly installments from February 1, 2018, through February 1, 2022, subject to the Reporting Person's continued service to the Company. The shares underlying this option vest in equal monthly installments from February 6, 2019 through February 6, 2023, subject to the Reporting Person's continued service to the Company. The shares underlying this option vest in equal monthly installments from February 5, 2020 through February 5, 2024, subject to the Reporting Person's continued service to the Company. The shares underlying this option vest in equal monthly installments from February 5, 2021, through February 5, 2025, subject to the Reporting Person's continued service to the Company. /s/ Danielle Holland, attorney-in-fact (power of attorney filed herewith) 2021-03-24